Inflammatory Bowel Disease and Eating Disorders: A systematized review of comorbidity

Abstract

Recent evidence suggests there is a possible association between Inflammatory Bowel Disease and Eating Disorders, although the mechanisms involved in its ethiopathogenesis are still unknown. To be aware of this association is important because a delayed diagnosis of this comorbidity may lead to worse prognosis. Further research and a multidisciplinary approach could facilitate earlier diagnosis and provide therapeutic interventions.

Bidirectional relationship between eating disorders and autoimmune diseases

“…For example, cortisol levels are dysregulated in EDs (Monteleone et al., ) possibly due to an altered stress response. Cortisol is often included in the therapeutic regimen for autoimmune diseases (Ilzarbe et al., ; Straub & Cutolo, ).…”

Anorexia Nervosa Complicating Pediatric Crohn Disease—Case Report and Literature Review

“…Five patients required intestinal resection, 2 developed toxic megacolon and 1 died from intestinal perforation. It is tempting to speculate how inflammatory bowel disease may be a risk factor for eating disorders, given the focus on diet, fear of abdominal pain, poor body image and poor emotional wellbeing, factors also noted in the patient in this report ( 7 ).…”

“…The incidence of CD amongst adolescent males is 7.4 per 100,00 and 6 per 100,000 females per year. Benchimol et al ( 5 ) Crohn disease should be considered in the differential diagnosis of AN, especially in younger patients ( 6 , 7 ).…”

Editorial: Pediatric Inflammatory Bowel Diseases: Looking to the Future

“…Anorexia nervosa, rather than Crohn disease, is more often considered as the potential cause of weight loss in young adults. The coexistence of both diagnoses may be associated with poor outcomes (4).…”