Inflammatory Bowel Disease and Pregnancy

Abstract

Long elimination half-life and should be stopped 3 mo before conception 6MP, 6-mercaptopurine; IL, interleukin; TNF, tumor necrosis factor.

Perspectives on promoting healthy pregnancies

“…For instance, the discriminatory structures and cultures faced by individuals with disabilities underscore the necessity for social support measures that protect maternal rights during pregnancy and childbirth [ 17 ]. Additionally, a multidisciplinary approach is currently being employed to tailor prepregnancy counseling recommendations for patients with inflammatory bowel disease, a common chronic condition [ 18 ]. Furthermore, individualized management plans for women diagnosed with cancer during pregnancy, as well as their families, have been formulated by care teams that include nurses [ 19 ].…”

Surgery in Pregnancy

“…Surgery is rarely necessary during pregnancy in patients with inflammatory bowel disease (IBD) and is generally reserved for severe refractory cases of ulcerative colitis (UC) and Crohn's disease and for associated complications (45) See Shmidt and Dubinsky's article on the management of IBD in pregnancy in this monograph (46). Experts agree that surgery should occur before the need for transfusion, perforation, or sepsis (47) because these complications are associated with high rates of fetal and maternal demise.…”

Clinical advances: pregnancy in gastroenterologic and hepatic conditions

“…Surgery is rarely necessary during pregnancy in patients with inflammatory bowel disease (IBD) and is generally reserved for severe refractory cases of ulcerative colitis and Crohn’s disease (CD) and for associated complications 29 30. In general, ileal pouch anal anastomosi procedures are performed electively after childbearing is over.…”