Inflammatory cells of teleostean fish: A review focusing on mast cells/eosinophilic granule cells and rodlet cells

Reite, Ola B.; Evensen, Øystein

doi:10.1016/j.fsi.2005.01.012

Cited by 292 publications

(307 citation statements)

References 77 publications

(101 reference statements)

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“…frino et al, 1999; Dezfuli et al, 2000a Dezfuli et al, , 2002a Dezfuli et al, , b, 2003b Bosi et al, 2005). The cellular involvement in the inflammatory response in teleostean fish could be biphasic, initiating with an influx of neutrophils followed by latter arrival of monocytes/macrophages (Reite & Evensen, 2006). In fish, two inflammatory cell types, namely mast cells and rodlet cells (RCs) are closely linked to other piscine inflammatory cells (Reite, 1997; Dezfuli et al, 2000b).…”

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“…These cells have been noticed in all vertebrates, fish (Roberts et al, 1971;Reite, 1996), amphibians (Chiu & Lagunoff, 1972), reptiles (Sottovia-Filho & Taga, 1973), birds (Selye, 1965) and mammals (Galli, 1990; Chiarini-Garcia & Pereira, 1999). Nevertheless, there is some controversy in the literature about mast cells existence in fish despite the fact that early reviews of the mast cells left little doubt that this cell type was present in all groups of vertebrates (Reite & Evensen, 2006). In fish parasitized with helminths, greater number of mast cells was noticed in site of infection (Reite, 1997; Dezfuli et al, 2000b;Reite & Evensen, 2006).…”

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The inflammatory response of fish to helminth parasites

Dezfuli¹,

Lui²,

Boldrini

et al. 2008

Parasite

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Summary :Fish serve as a good model for studying vertebrate immune systems because they have a relatively simple system. Descriptions of histopathological effects of helminth parasites on fish are few and far between with limited observations made on the identification of the inflammatory cells involved in the host reaction. Recently, two cell types found within teleosts received a great deal of attention, namely mast cells and rodlet cells. Fish mast cells also known as eosinophilic granule cells, are morphologically and functionally similar to their mammalian counterparts. Acute tissue damage causes mast cells degranulation and the release of mediators of inflammation, whereas, an increase in the number of these cells is usually found in chronically inflamed tissues. Rodlet cells, however, are exclusive to fish and are characterized by a distinct cell cortex and conspicuous inclusions, called rodlets, which accounts for their name. Piscidin has also been encountered within rodlet cells. As important cell types within the immune system of fish, both mast cells and rodlet cells have been seen to increase in number in infected fish, notably at the sites of pathogen attachment or infection. The present survey will provide data from studies with the light microscope on the response of mast cells and rodlet cells in a range of fish species (Anguilla anguilla, Oncorhynchus mykiss, Salmo trutta, Coregonus lavaretus) infected with a range of different parasite genera including representatives from the Digenea, Cestoda, Nematoda and Acanthocephala. frino et al., 1999; Dezfuli et al., 2000a Dezfuli et al., , 2002a Dezfuli et al., , b, 2003b Bosi et al., 2005). The cellular involvement in the inflammatory response in teleostean fish could be biphasic, initiating with an influx of neutrophils followed by latter arrival of monocytes/macrophages (Reite & Evensen, 2006). In fish, two inflammatory cell types, namely mast cells and rodlet cells (RCs) are closely linked to other piscine inflammatory cells (Reite, 1997; Dezfuli et al., 2000b). Mast cells are found mainly in the connective tissue distributed throughput the body, and are more frequently found in tegumentary, urinary, respiratory, reproductive and gastrointestinal systems (Rocha & Chiarini-Garcia, 2007). These cells have been noticed in all vertebrates, fish (Roberts et al., 1971;Reite, 1996), amphibians (Chiu & Lagunoff, 1972), reptiles (Sottovia-Filho & Taga, 1973), birds (Selye, 1965) and mammals (Galli, 1990; Chiarini-Garcia & Pereira, 1999). Nevertheless, there is some controversy in the literature about mast cells existence in fish despite the fact that early reviews of the mast cells left little doubt that this cell type was present in all groups of vertebrates (Reite & Evensen, 2006). In fish parasitized with helminths, greater number of mast cells was noticed in site of infection (Reite, 1997; Dezfuli et al., 2000b;Reite & Evensen, 2006). Regarding rodlet cells (RCs), they are characterized by a thick fibrous capsule, a basal nucleus, and conspicuous in...

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confidence: 99%

mentioning

confidence: 99%

The inflammatory response of fish to helminth parasites

Dezfuli¹,

Lui²,

Boldrini

et al. 2008

Parasite

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“…Funcionalmente, as EGCs dos teleósteos são similares aos mastócitos dos mamíferos, isto é, são mediadores do processo inflamatório. A degranulação das EGCs é seguida por uma reação inflamatória com vasodilatação (Reite & Evensen, 2006). Estudos sobre o efeito de plantas em tilápias nilóticas já foram realizados por outros autores.…”

Section: Discussionunclassified

Efeito do extrato etanólico bruto e das frações da Hyptidendron canum (Pohl ex Benth.) Harley em brânquias de Oreochromis niloticus L.

Fiuza

Silva

Paula

et al. 2015

Rev. bras. plantas med.

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RESUMO:Alguns problemas relacionados à criação intensiva de peixes estão mais evidentes devido ao aumento da aquicultura em todo o mundo, destacando-se os distúrbios nutricionais e o aumento de doenças nos sistemas de produção. Com isso as pesquisas envolvendo produtos derivados de plantas vem ganhando espaço nessa área. A Hyptidendron canum é uma planta utilizada na medicina popular como antimalárica, anti-inflamatória, antiulcerativa e anti-hepatotóxica. Objetivou-se, neste trabalho, avaliar os efeitos celulares e teciduais do extrato etanólico bruto e das frações hexano, clorofórmio e acetato de etila da H. canum nas brânquias de Oreochromis niloticus L. Para isso, o extrato etanólico e as frações foram administrados no peixe através da ração. Após 24 horas da ingestão da ração, os peixes foram sacrificados e o segundo arco branquial de cada um foi processado histologicamente e corado com tricômico de Masson e Hematoxilina e Eosina (HE). Pela análise qualitativa das brânquias ao microscópio de luz, observou-se que o extrato bruto e as três frações promoveram, em diferentes intensidades nas lamelas, descamação e destacamento do epitélio respiratório, alteração da curvatura, desorganização do eixo, hiperplasia celular do tecido epitelial interlamelar e vasodilatação nas lamelas e no vaso central do filamento. Os resultados deste experimento mostraram que o extrato etanólico bruto e as três frações de H. canum promoveram processos inflamatórios e/ou lesões sistêmicas, dose dependente para O. niloticus. Palavras-chave:Cerrado, plantas medicinais, tilápia, toxicidade. ABSTRACT: Effect of the crude ethanol extract and fractions of Hyptidendron canum(Pohl ex Benth.) Harley on the gills of Oreochromis niloticus L. Some problems related to intensive fish farming are more evident because of the increased aquaculture worldwide, and we highlight the nutritional disorders and the increase of diseases in the production systems. Thus, research involving plant-derived products has been increasing in this area. The Hyptidendron canum is a plant used in folk medicine as an antimalarial, anti-inflammatory, anti-ulcer and antihepatotoxic agent. This study proposes to evaluate the cellular and tissue effects of the crude ethanol extract and the hexane, chloroform and ethyl acetate fractions of H. canum on the gills of Oreochromis niloticus L. The ethanol extract and fractions were administered through the feed of the fish. Twenty-four hours later, the fish were sacrificed and their second gill arch dissected. Histological analyses were performed using Masson's trichrome and Haematoxylin and Eosin (H&E). The qualitative analysis of the material showed that the crude extract and the three fractions caused varying degrees of peeling and detachment of the lamellar respiratory epithelium, alterations in the curvature and axis of the gill, cell hyperplasia in the interlamellar epithelium and lamellar vasodilation, as well as vasodilation in the central vessel of the filament. The results of this experiment showed that the crude ethanol...

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“…Moreover, LIR was located in the cytoplasm of a particular cell type in the gastrointestinal lamina propria of teleosts: EGCs (Ezeasor & Stokoe 1980;Bergeron & Woodward 1982, 1983. These eosinophilic granulocyte cells or, most probably, mast cells, are considered to be mediators of inflammation processes (Reite 1998;Reite & Evensen 2006). EGCs showed different morphologies, distributions and densities depending on the studied species (Rocha & Chiarini-Garcia 2007).…”

Section: Discussionmentioning

confidence: 99%

Immunolocalisation of leptin in the digestive system of juvenile European sea bass (Dicentrarchus labrax)

Gambardella

Ferrando

et al. 2010

Italian Journal of Zoology

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Leptin is a hormone that is mainly produced by adipocytes; it is connected with metabolism regulation, but knowledge about its effect on teleosts, particularly in juvenile specimens, is still scarce. This study is the first to investigate the presence of leptin immunoreactivity in juvenile European sea bass (Dicentrarchus labrax) and its distribution in the digestive system. Leptin immunoreactivity was detected by Western blot analysis, while its distribution was obtained using immunohistochemical methods with a human leptin-specific antibody. The homogenate of the body of a whole European sea bass contains a leptin-like protein with an estimated molecular weight of approximately 16 kDa. Leptin immunoreactivity was distributed along the digestive system, especially in the oesophageal mucous cells, neuroendocrine gastrointestinal cells and eosinophilic granular cells of the gastrointestinal lamina propria. This is the first report on leptin immunoreactivity in juvenile sea bass and our data can provide a good morphological basis for further investigation into food, metabolism and immunoresponse regulation in aquacultured fish.

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Inflammatory cells of teleostean fish: A review focusing on mast cells/eosinophilic granule cells and rodlet cells

Cited by 292 publications

References 77 publications

The inflammatory response of fish to helminth parasites

The inflammatory response of fish to helminth parasites

Efeito do extrato etanólico bruto e das frações da Hyptidendron canum (Pohl ex Benth.) Harley em brânquias de Oreochromis niloticus L.

Immunolocalisation of leptin in the digestive system of juvenile European sea bass (Dicentrarchus labrax)

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