Inflammatory fibroid polyp (Vanek’s polyp): a case report and literature review

Intestinal Intussusception in an Adult Affected by Vanek Tumor: A Case Report

“…Other sites in descending order are colon, jejunum, duodenum, and esophagus. Rarely it reaches more than 6cm, however there is a case of IFP reported with 12.5cm diameter [3]. Most of the studies correspond to cases reports.…”

“…The IFP is a benign lesion that arises from the submucosa of the gastrointestinal (GI) tract, most commonly in the antrum (70%) and ileum (20%) and, only occasionally, in the duodenum and jejunum. Its frequency from 1% to 4% of diagnoses among benign lesions, and usually occurs between the fifth and the seventh decade of life [3]. The underlying cause of IFPs is still unknown.…”

Multiple Inflammatory Fibroid Polyps in a Female; A case Report

“…Later it became recognized by different names; eosinophilic granuloma, inflammatory pseudotumor and Vanek polyps. 3 IFPs occur most commonly in stomach followed by small intestine leading to intestinal obstruction with a slight predominance in males. 1 IFP lesion causes intussusception which is the main cause of intestinal obstruction, however the sign and symptoms differ according to the site of origin.…”

“…in exon 12 or 18 and, less frequently, in exon 14 of platelet derived growth factor receptor alpha gene indicating a possible neoplastic etiopathogenesis of the lesion. 3 There are numerous case reports of solitary IFP, but there are very few case reports of patients presenting with multiple inflammatory fibroid polyps (IFPs).We are presenting our case report of multiple IFPs in a female patient with the review of literature.…”

“…1,2 Vanek was the first to describe it as eosinophilic submucosal granuloma followed by Helwing who established the term inflammatory fibroid polyp in 1953. 3 These polyps occur more commonly in males, and stomach is the favored site followed by ileum, colon and duodenum. 1 Morphologically, IFP shows spindle cell proliferation with marked eosinophilia and prominent small blood vessels.…”