Inflammatory markers as predictors of late-onset fetal growth restriction: a focus on neutrophil-to-lymphocyte and platelet-to- lymphocyte ratios

Abstract

Aim: This study evaluates the role of hematologic inflammatory markers, specifically neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), in predicting late-onset fetal growth restriction (FGR). Material and Methods: A retrospective comparative analysis was conducted on 76 pregnancies complicated by late- onset FGR and 100 healthy pregnancies as controls. Maternal blood samples were collected, and hematologic parameters, including NLR and PLR, were recorded. Data analysis compared inflammatory markers between the FGR and control groups to assess the relationship between maternal inflammatory profiles and FGR. Results: NLR was significantly higher in the FGR group compared to the control group (p