Inflammatory Myofibroblastic Tumor Arising in the External Ear : Unexpected Location

Alhumidi, Ahmed; Alkhamiss, Abdullah

doi:10.12816/0024128

Cited by 9 publications

(17 citation statements)

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“…There is a positive expression with vimentin, actin and rarely desmine in the tumor cells [2,5,10,14]. In our case, vimentin and SMA was diffuse positive and desmine was focal weakly positive.…”

Section: Introductionmentioning

confidence: 54%

“…Necrosis and calcification may rarely occur [1]. Focal cellular atypia and mitosis can be seen, but no atypical mitosis is expected [2,10]. In our case, a cellular tumor forming fascicular and storiform patterns was observed.…”

Section: Introductionmentioning

confidence: 58%

“…According to the classification of the World Health Organization (2002), IMT was classified as a tumor with potential of intermediary malignancies and rare metastasis [5,9]. It was called inflammatory pseudotumor in the past years since it might behave as act malignant clinically, radiologically and microscopicaly [10]. The average age of patients with IMT is 9 and it is often seen in…”

Section: Discussionmentioning

confidence: 99%

“…Although IMT can occur in many different anatomical regions, it is most frequently seen in the lungs of the respiratory system followed by abdominopelvic region and retroperitoneum [5,6,10]. Tracheal involvement is rare.…”

Section: Introductionmentioning

confidence: 99%

“…In our case, no ALK positivity was found. In several studies, ALK negative IMTs showing more aggressive clinical behaviors due to the increased risk of metastasis and local recurrence are reported [1,5,10,13,14]. This suggests that detection of ALK with immunohistochemical method may be used to determine the prognosis.…”

Section: Introductionmentioning

confidence: 99%

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Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

Fındık¹,

AltinokT²

2017

JLPRR

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Inflammatory myofibroblastic tumor is a rare tumor with intermediate potential of malignancy usually encountered in children and young adults and located in respiratory system, abdominopelvic and retroperitoneal areas. The most commonly seen in the lungs in respiratory system, trachea involvement is rare. Etiology and pathogenesis of IMT is still uncertain. IMT can mimic various benign or malignant tumors due to absence of specific clinical or radiologic findings. In this study, we presented a case of tracheal IMT detected in a 6 years old girl and discussed its clinical and pathological characteristics.

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Section: Introductionmentioning

confidence: 54%

Section: Introductionmentioning

confidence: 58%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

Fındık¹,

AltinokT²

2017

JLPRR

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Case report of an unexpected inflammatory myofibroblastic tumor

Raza

Arshad

Ahmad

et al. 2021

Annals of Medicine &Amp; Surgery

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Introduction Inflammatory myofibroblastic tumor is a benign entity that may present as a locally aggressive malignancy, predominantly in the lung. 500 cases have been reported in the literature, and an estimated prevalence ranges from 0.04% to 0.7%. Case presentation An eighteen-year old male presented to the surgical clinic with abdominal pain. The pain was recurring despite trials of analgesics and remained undiagnosed. Radiological imaging demonstrated a lesion in the spleen. An infectious cause was presumed due to their endemicity in South Asia, however pathology showed an inflammatory myofibroblastic tumor. Discussion Pre-operative imaging is yet to develop a set criterion that may identify this lesion, though clinicians may be clued in by the benign appearance despite the large size. Usual diagnosis is on pathology after complete surgical excision, which is the mainstay treatment advocated. Conclusion Reporting of the tumor in unusual sites such as the spleen is scarce, increase of which may help establish guidelines, understand tumor behavior and guide clinicians that may encounter it in surgical practice.

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Rare presentation of inflammatory myofibroblastic tumor on a digit

et al. 2021

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Inflammatory myofibroblastic tumors (IMTs) are rare soft tissue neoplasms consisting of a mixture of spindle‐shaped myofibroblasts or fibroblasts and a variable inflammatory infiltrate composed of eosinophils, plasma cells, and lymphocytes. Associations with trauma and infectious agents have been proposed, but the etiology is unknown. While IMT predominantly develops in the lungs of pediatric patients or young adults, extrapulmonary IMT is well documented and may occur anywhere. Cutaneous IMT is rare and few have been reported on the hand in the English language. The mean age of onset is 10 years, with a slight female predilection. IMT demonstrates intermediate malignant potential, with a tendency to recur locally. Metastases are rare. According to a recent review, anaplastic lymphoma kinase (ALK) positivity on immunohistochemistry is related to local recurrence, but not distant metastases. We report an unusual case of a 36‐year‐old male, with a lesion on the right second digit, displaying classic histopathologic and immunohistochemical features of IMT, including ALK staining, and confirmatory fluorescence in situ hybridization‐proven ALK gene rearrangement.

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Inflammatory Myofibroblastic Tumor Arising in the External Ear : Unexpected Location

Cited by 9 publications

References 0 publications

Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

Case report of an unexpected inflammatory myofibroblastic tumor

Rare presentation of inflammatory myofibroblastic tumor on a digit

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