Inflammatory myofibroblastic tumor associated with renal cell carcinoma

Gwynn, Eric S; Clark, Peter E.

doi:10.1016/j.urology.2005.03.065

Cited by 18 publications

(20 citation statements)

References 7 publications

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“…The absence of significant nuclear pleomorphism in the spindle cell component, absence of a biphasic appearance with another typical pattern of renal-cell carcinoma, and lack of evidence for epithelial differentiation by immunohistochemistry were against an interpretation of sarcomatoid RCC in our case. [1011]…”

Section: Discussionmentioning

confidence: 99%

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Inflammatory myofibroblastic tumor of kidney with heterotopic bone formation: An unusual case mimicking a renal malignancy

Navale

Menon

Bakshi

et al. 2013

Indian Journal of Medical and Paediatric Oncology

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Inflammatory myofibroblastic tumor (IMFT) or pseudotumor is a rare tumor that can be seen in various organs. It is an enigmatic tumor of unknown etiology and difficult to differentiate from malignancy, clinically as well as radiologically. Histologically, it is composed of variable proportions of proliferating spindle myofibroblasts, fibroblasts, extracellular collagen, lymphocytes and plasma cells. This mainly affects the urinary bladder or prostate. Renal involvement is extremely rare and may pose diagnostic difficulty to the clinician. We describe a renal IMFT, mimicking renal malignancy, having unusual histological features.

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Section: Discussionmentioning

confidence: 99%

“…[3] Nevertheless, such cases have to be closely followed-up since there is evidence in the literature demonstrating association of RCC arising in a background of inflammatory pseudotumor of kidney. [11]…”

Section: Discussionmentioning

confidence: 99%

Inflammatory myofibroblastic tumor of kidney with heterotopic bone formation: An unusual case mimicking a renal malignancy

Navale

Menon

Bakshi

et al. 2013

Indian Journal of Medical and Paediatric Oncology

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“…Some authors reported malignancy associated with inflammatory pseudotumors [9] and it is difficult to make a preoperative diagnosis because symptoms and imaging findings are not specific. It is therefore appropriate to presume the given renal mass to be a renal cell carcinoma and to perform nephrectomy (be it radical or partial).…”

Section: Discussionmentioning

confidence: 99%

Inflammatory pseudotumor of the kidney: a case report

et al. 2011

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IntroductionInflammatory pseudotumors, also known as inflammatory myofibroblastic tumors, are uncommon benign tumors of unknown etiology which may develop at several anatomical sites. In the urogenital tract, inflammatory pseudotumor usually affects the urinary bladder or the prostate. Inflammatory pseudotumor of the kidney is very rare. It is considered as a reactive inflammatory lesion that features very good prognosis.Case presentationWe present the case of a 57-year-old Moroccan man who presented with a two-month history of gross hematuria and left lumbar pain. Imaging investigations revealed a left kidney mass and pathological examination of the nephrectomy specimen showed an inflammatory pseudotumor.ConclusionAs the preoperative definitive diagnosis of such a tumor is not possible, surgery is advised because only pathological examination of the nephrectomy specimen can establish the diagnosis with certainty. From one case report and literature review, the authors suggest a diagnostic and therapeutic strategy for the management of this rare tumor.

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“…Almost diagnoses have been made at the time of surgical intervention. Eric et al (6) demonstrate the first reported association of malignancy with IMT in the urogenital tract and the necessity for surgical excision. Therefore, preoperative exclusion of malignancy is very difficult and there is a risk that this lesion could be misdiagnosed such as renal cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory Myofibroblastic Tumor of the Kidney Misdiagnosed as Renal Cell Carcinoma

Ryu

Kim

et al. 2010

J Korean Med Sci

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The inflammatory myofibroblastic tumor (IMT), also knowns as inflammatory pseuduotumor, is a soft tissue lesion of unknown etiology. In the urogenital tract, IMT mainly affects the urinary bladder or prostate, but rarely the kidney. It has been considered as a nonneoplastic reactive inflammatory lesion, but nowadays, it is regarded as a neoplasm due to its high recurrence rate and metastasis. We describe a case of a 61-yr-old woman that had originally been misdiagnosed as renal cell carcinoma, which was pathologically revealed to be an IMT.

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Inflammatory myofibroblastic tumor associated with renal cell carcinoma

Cited by 18 publications

References 7 publications

Inflammatory myofibroblastic tumor of kidney with heterotopic bone formation: An unusual case mimicking a renal malignancy

Inflammatory myofibroblastic tumor of kidney with heterotopic bone formation: An unusual case mimicking a renal malignancy

Inflammatory pseudotumor of the kidney: a case report

Inflammatory Myofibroblastic Tumor of the Kidney Misdiagnosed as Renal Cell Carcinoma

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