Inflammatory myofibroblastic tumor of jejunum in a child

Liaqat, Naeem; Tasneem, Sadia; Imran, Raja Muhammad; Kanwal, Ammara; Gondal, Mudassar Fiaz; Jamil, Sadia

doi:10.1016/j.epsc.2019.101313

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Immunohistochemical analysis reveals inflammatory cells that express benignity, as opposed to malignant cells that are polyclonal. Cells positive for actin, smooth muscle, vimentin and desmin, in 33–67% of cases the cells are positive for ALK, which is present in some malignant lesions [ 17 , 28 ]. Ultrastructurally, a myofibroblastic component with abundant rough endoplasmic reticulum, cytoplasmic filaments and dense bodies is demonstrated [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Inflammatory myophibroblastic tumor of the proximal ileon in a patient with complicated umbilical hernia: A case report and literature review

Romero

Cárdenas²,

Vázquez

et al. 2021

International Journal of Surgery Case Reports

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Introduction Inflammatory myofibroblastic tumors are neoplasms that occur infrequently, mainly affects children and young adults. It is an intermediate grade fibrotic multinodular neoplasm. Description of the case We present the case of a 47-year-old female patient, who underwent emergency umbilical hernioplasty, later developed intestinal obstruction secondary to an inflammatory myofibroblastic tumor. Discussion In 1939 Brunn described it for the first time, later in 1954 Umiker named it “Inflammatory Myofibroblastic Tumor”. The symptoms are nonspecific. In 15 to 40% of patients they are asymptomatic. Cells positive for actin, smooth muscle, vimentin and desmin, in 3367% of cases the cells are positive for ALK, which is present in some malignant lesions. The recommended treatment is radical resection. Conclusion The diagnosis is established by histopathological study, surgery is the cornerstone of treatment.

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Section: Discussionmentioning

confidence: 99%

Inflammatory myophibroblastic tumor of the proximal ileon in a patient with complicated umbilical hernia: A case report and literature review

Romero

Cárdenas²,

Vázquez

et al. 2021

International Journal of Surgery Case Reports

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An extremely rare case of malignant jejunal mesenteric inflammatory myofibroblastic tumor in a 61-year-old male patient: A case report and literature review

et al. 2022

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IntroductionA mesenteric inflammatory myofibroblastic tumor (IMT) is a rare solid tumor of intermediate malignant potential that affects children, adolescents, and young adults predominantly. IMT is mostly encountered in the lung. We report a case of malignant jejunal mesenteric IMT in a 61-year-old male patient who presented with vague abdominal pain and generalized weakness. CT scan revealed a mesenteric mass displacing the attached jejunum. Surgical resection was curative.DiscussionAn extensive literature review was performed to update and further analyze the already available data. A total of 35 cases with mesenteric IMT were reported previously. Only five cases of jejunal mesenteric IMT were reported. Mesenteric IMT demands vast effort to reveal the diagnosis due to its vagueness in the clinical presentation. Mesenteric IMT resembles each other in plenty of pathological and immunohistochemical characteristics.ConclusionTo the best of our knowledge, this is the first case of malignant jejunal mesenteric IMT in the elderly. Surgical resection was curative.

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Inflammatory myofibroblastic tumor of jejunum in a child

Cited by 2 publications

References 8 publications

Inflammatory myophibroblastic tumor of the proximal ileon in a patient with complicated umbilical hernia: A case report and literature review

Inflammatory myophibroblastic tumor of the proximal ileon in a patient with complicated umbilical hernia: A case report and literature review

An extremely rare case of malignant jejunal mesenteric inflammatory myofibroblastic tumor in a 61-year-old male patient: A case report and literature review

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