Inflammatory Myofibroblastic Tumor of the Lung: Unusual Imaging Findings

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm, most commonly seen in children and adolescents. It can occur in nearly every part of the body. Imaging properties and the clinical presentation of IMT can mimic malignant process. A 41-year-old female presented with cough of 3 months duration. Chest X-ray showed a coin shadow in the right upper lobe. Positron emission tomography/computed tomography scan showed a 3.2 × 2.4 cm lesion with homogeneous appearance with a very high fluorodeoxyglucose uptake value, suggesting a neoplastic process. She underwent lobectomy and the final diagnosis was IMT.

The Right Inferior Pulmonary Vein Related Inflammatory Myofibroblastic Tumor in an Adult Case

“…IMT, which is a rare tumor of mesenchymal origin, can be seen in nearly everywhere in the body [8]. Macroscopic findings of our case suggested that it may have been resulted from RIPV (Figure 3).…”

“…Macroscopic findings of our case suggested that it may have been resulted from RIPV (Figure 3). No matter where it originates from, the main treatment of IMT is surgical excision [1][2][3]8]. The efficiency of nonsurgical treatments has not been established [3].…”

A case of inflammatory pseudotumor of the lung presenting as polymyalgia rheumatica

“…In the lung, these lesions may be parenchymal or endobronchial. Considered cellularly benign, they rarely invade the mediastinum, but can impinge on nearby structures . These lesions also have the potential to recur, which is thought to be due primarily to incomplete resection …”

“…Though there are case reports of complete resolution of inflammatory pseudotumors of the lung with pharmacotherapy, complete surgical resection remains the most frequently recommended course of treatment . Resection is performed both to exclude malignancy and to achieve cure as local expansion can cause morbidity . If the lesion is unable to be completely resected, cannot be resected due to location or size, or in the case of multifocal disease, reported treatments have included radiotherapy, chemotherapy, and corticosteroids .…”

“…Considered cellularly benign, they rarely invade the mediastinum, but can impinge on nearby structures. 13 These lesions also have the potential to recur, which is thought to be due primarily to incomplete resection. 6 Inflammatory pseudotumors of the lung are relatively rare, especially in adults, and are thought to represent <1% of all reported lung lesions.…”