Inflammatory Myofibroblastic Tumor of the Breast

Abstract

Inflammatory myofibroblastic tumors (IMTs) of the breast represent extremely rare lesions. Due to the scarcity of reports, their natural history, recurrence, and metastatic potential remain poorly defined. We report on a case of a primary breast IMT in a postmenopausal female patient treated successfully with breast conserving surgery and review the literature pertaining to this rare entity.

Inflammatory Myofibroblastic Tumor of the Trachea: A Case Report and Review of the Literature

“…The presence of inflammatory cells were also helpful in differential diagnosis. In the pathogenesis of disease, the role of mutation of anaplastic lymphoma kinase (ALK) gene was shown and there is a cytoplasmic positivity with ALK immunohistochemically in about 50% of the cases [5,7,14,15]. In our case, no ALK positivity was found.…”

“…IMT is a rare mesenchymal tumor that is still not fully understood in terms of its etiology and pathogenesis [6,7]. According to several studies conducted in recent years, infection, surgery, trauma and chromosomal variations may have a role in the development of IMT and there are localized deviations in chromosome 2 and 9 [6,8].…”

Clinicopathological Features of Inflammatory Myofibroblastic Tumor in the Breast

“…e BI-RADS classification is mostly above grade 4A [18,19,24,26,27]. MRI shows that the mass is irregular, with uneven and rapid enhancement, and mostly demonstrates the morphological and hemodynamic characteristics of breast malignant tumors.…”

Imaging findings of inflammatory myofibroblastic tumors in the breast: a case description and literature analysis

“…Therefore, there is no systematic description or summary of its imaging features in the literature, and most of them are reported on the imaging performance of ultrasound and mammograms (17)(18)(19)(20). There is also no characteristic imaging appearance of the disease on ultrasound and mammography.…”