Inflammatory Myofibroblastic Tumor of the Lung

Abstract

We report a case of a patient with inflammatory myofibroblastic tumor of the lung, which recurred after steroid treatment. The diagnosis of the tumor was confirmed by a core needle lung biopsy and pathology. The patient was initiated on steroid therapy, which on complete response was slowly tapered and discontinued. Few months later, the patient presented with dyspnea again. Chest radiography and computed tomography scans depicted recurrence at the tumor resection site in the right lobe of lung and a new tumor in the left lower lobe. Restarting the steroid therapy, led to regression of the tumors at both sites. This is a rare case of inflammatory myofibroblastic tumor recurring poststeroid therapy and adds to the current clinical knowledge about this peculiar manifestation of this disease entity.

Immunoglobulin G4 related systemic sclerosing disease involving the temporal bone

“…[20][21][22][23] However, there are cases of patients being treated with corticosteroids alone, with good results. 6 This case could also support an argument for the use of other immunosuppressive agents. 6 This case could also support an argument for the use of other immunosuppressive agents.…”

Contralateral recurrence of inflammatory myofibroblastic tumour of the lung 10 years after pneumonectomy

“…Recurrent contralateral disease has been reported in patients undergoing complete resection without pneumonectomy,3 but we believe this case presents a unique entity, as recurrent disease in a solitary lung presents a management dilemma due to limited surgical options. Prior case reports and case series have shown corticosteroids to stabilise disease and even induce remission 2. Due to the low recurrence rate after complete resection, it remains unknown if empiric medical therapy postsurgery could prevent long-term recurrence.…”

Diagnostic and Therapeutic Challenges of a Large Pleural Inflammatory Myofibroblastic Tumor

“…Most patients can be cured by complete surgical resection, but some lesions become locally invasive and involve the mediastinum, diaphragm, chest wall, vertebral bodies, heart, and major vessels. For patients with progressive disease and unable to have complete surgical resection (e.g., poor surgical candidates, multiple nodules, or unresectable disease), glucocorticoids, radiotherapy, chemotherapy, anti-inflammatory, and immunomodulatory concepts have been used with variable success [7, 19, 20]. In the case presented, due to residual postoperative disease, IVIGs have been administered.…”