Inflammatory Myofibroblastic Tumor of the Bladder: 2 Rare Cases Managed with Laparoscopic Partial Cystectomy

Abstract

Two cases of inflammatory myofibroblastic tumor (IMT) of the bladder are reported here. Both patients were male and presented with macroscopic hematuria; in the first case terminal hematuria was associated with irritative voiding symptoms. The second case was a smoker with hematuria unresponsive to medical treatment and anemia. Clinical presentation, pathological features, treatment, and prognosis are discussed. Due to rarity of this pathological condition, there are no guidelines concerning treatment and follow-up. We present our follow-up scheme and highlight the use of laparoscopic partial cystectomy as a successful treatment approach.

Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour

“…There are no standardized schemes regarding follow-up, but it is advisable since this tumour has 25% recurrence. However, given the indeterminate biological behavior of these tumours, continued monitoring of their clinical course is strongly recommended [11] .…”

Inflammatory myofibroblastic tumor of the urinary bladder: A systematic review of the literature and report of a case

“…We compared the results of published case reports to collate the existing evidence derived from retrospective cohorts and case series. [ 24 25 26 27 28 29 30 31 32 ] Despite that, the literature remains scarce regarding the optimal diagnosis, management, and follow-up protocol for IMTs of the bladder. The largest systematic review on the topic included 182 patients, but included both the IMTs and pseudosarcomatous myofibroblastic proliferation of the bladder.…”

“…In cohort studies and case series,[ 24 25 26 27 28 29 30 31 32 ] the age of the patients diagnosed with bladder IMTs ranged between 3 and 89 years (mean age of 44 years), and the most common clinical presentation was gross hematuria, in more than 60% of the cases. While the pathological type was variable, the most common type of bladder IMT was the spindle cell pattern [ Table 1 ].…”

A rare noncancerous but life‐threatening tumor in urinary bladder

“…2,6,7 Sofia et al have reported 2 cases treated with laparoscopic partial cystectomy to achieve total resection, and no recurrence was noted after 58 months of follow-up. 6 However, there are no studies regarding a safety margin during partial cystectomy in cases of IMTs, and although it is required to achieve free resection margins, the benefit of negative margin resection must be weighed against the bladder capacity and function preservation in patients whose tumor invades only superficial layer and are of relatively old age. Teoh et al's have conducted a systemic review, and among the 182 patients, 60.8% were treated with TURBT and they indicated that most cases can be adequately treated with transurethral resection.…”

“…In the consideration of complete local resection, the treatment option includes TURBT and partial cystectomy. Concerning the possibility of local recurrence, partial cystectomy is often the treatment option to ensure total resection of the tumor 2,6,7 . Sofia et al have reported 2 cases treated with laparoscopic partial cystectomy to achieve total resection, and no recurrence was noted after 58 months of follow‐up 6 …”