Inflammatory Myofibroblastic Tumor of the Sigmoid Colon in an Infant: A Case Report and Literature Review

Wu, Luyao; Meng, Xinyao; Wang, Jing; Wang, Qiong; Sun, Xiuting; Zhu, Tianqi; Yu, Dunxi; Feng, Jiexiong

doi:10.1080/15513815.2022.2062500

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…One case of IMT in the transverse colon was also reported 7. To our knowledge, there are only eight reported cases of IMT arising from the sigmoid colon 4. In all these cases, the mass mostly involved both the sigmoid and the mesentery.…”

Section: Discussionmentioning

confidence: 94%

“…IMT, first described in 1937,2 is currently used as an umbrella terminology for a myriad of different conditions such as plasma cell granuloma, inflammatory pseudotumor and inflammatory fibroid tumour 3. They are usually seen in children and young adults, however, a few cases have also been reported in infants 4. IMTs can be found in a variety of anatomic sites, the most popular being lungs.…”

Section: Discussionmentioning

confidence: 99%

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Infantile inflammatory myofibroblastic tumour of the sigmoid colon: a diagnostic dilemma

Kavirayani,

Pai,

Nayal

et al. 2023

BMJ Case Rep

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An inflammatory myofibroblastic tumour (IMT) is an uncommon neoplasm composed of inflammatory cells and myofibroblasts in a fibrous stroma. They are mostly seen in the lungs and rarely involve the gastrointestinal tract. An 8-month-old infant presented with a history of lower abdominal lump for 2 months. Her CT scan confirmed a large, lobulated mass in the retroperitoneum arising from the pelvis. The mass was found to be arising from the sigmoid colon on laparotomy which was excised. Histopathology showed a cellular tumour composed of spindle cells and inflammatory lymphocytic infiltrate. Immunohistochemistry revealed positive staining for anaplastic lymphoma kinase and smooth muscle actin, confirming the diagnosis of IMT. The patient is doing well at her 6-month follow-up. Ours is the youngest case of sigmoid IMT among the only other series of eight cases reported in the literature indicating its rarity.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Infantile inflammatory myofibroblastic tumour of the sigmoid colon: a diagnostic dilemma

Kavirayani,

Pai,

Nayal

et al. 2023

BMJ Case Rep

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Imaging findings of inflammatory myofibroblastic tumor of sigmoid colon: literature review and case report

Hu,

Zhao,

et al. 2024

Front. Med.

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Inflammatory myofibroblastic tumor (IMT) is an intermediate tumor composed of differentiated myofibroblastic spindle cells with inflammatory cell infiltration. It can occur in all parts of the body, with the lungs being the most common, while the tissues outside the lungs, including the sigmoid colon, are rare. Herein, we present a case of a 10-year-old girl with sigmoid IMT who presented to our hospital with abdominal pain. An abdominal computed tomography (CT) revealed a well-defined, slightly low-density mass in her lower abdomen that was not clearly demarcated from the sigmoid colon. The mass showed significant uneven enhancement on contrast-enhanced CT and increased fluorine-18 fluorodeoxyglucose (18F-FDG) uptake on positron emission tomography (PET). Moreover, a systematic review of the published literature on sigmoid IMT was conducted and its clinical and radiographic features were summarized to increase the understanding of this rare disease.

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Inflammatory Myofibroblastic Tumor of the Sigmoid Colon in an Infant: A Case Report and Literature Review

Cited by 2 publications

References 21 publications

Infantile inflammatory myofibroblastic tumour of the sigmoid colon: a diagnostic dilemma

Infantile inflammatory myofibroblastic tumour of the sigmoid colon: a diagnostic dilemma

Imaging findings of inflammatory myofibroblastic tumor of sigmoid colon: literature review and case report

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