Inflammatory Profile in Novel Coronavirus Infection: Biochemical Perspective

Abstract

The whole world is reeling under the coronavirus disease-2019 COVID-19 pandemic. It is caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 SARS-CoV-2. The diagnosis of COVID-19 is based on clinical manifestations history of exposure positive findings on chest computerized tomography CT and laboratory tests. It has been reported that increased release of pro-inflammatory mediators due to an overactive immune system plays a pivotal role in the pathogenesis of COVID-19. This review provides an insight into the different types of coronavirus strains and inflammatory profile involved in COVID-19 with special emphasis on biomarkers such as procalcitonin lactate dehydrogenase LDH ferritin D-dimer and cytokines.