Inflammatory Pseudotumor in the Lateral Ventricle with Repeated Bleeding-Case Report-

Abstract

Inflammatory pseudotumor is an uncommon lesion with unknown etiology characterized by sclerosing inflammation which clinically and radiographically mimics a neoplastic lesion. A 47-year-old man presented with sudden headache and dysarthria. Brain CT scan revealed a 2.6× 2.2 cm sized, round, and hyperdense mass in the anterolateral wall of the left lateral ventricular trigone. On MR imaging studies, the mass showed low signal intensity in the wall of the trigone on T2-weighted image, central mixed (iso-and high-) signal intensity with peripheral lowsignal intensity on T1-weighted image. Subtle staining of left choroid plexus with irregular shaped distal branch of anterior choroidal artery was found on the cerebral angiography. These findings suggested a small tumorous lesion originated from the left choroid plexus. During the hospital days, the mass manifested as repeated hemorrhages. The mass was successfully removed via left occipital transcortical approach. The histopathological report of the specimen was hemorrhage and fibrosis, with dense lymphoplasma cell infiltration, suggestive of an inflammatory

Central nervous system marginal zone B-cell lymphoma associated with Chlamydophila psittaci infection

“…In the present case, the tumor developed close to choroid plexus, and lymphoid cells were in close association with the epithelium, with features reminiscent of lymphoepithelial lesions; the lymphoid infiltrate was characterized by a diffuse, monomorphic-appearing medium-sized lymphocytes, which invariably displayed B-cell phenotype as well as coexpression of IgM. Although we were unable to document a monoclonal B-cell population, we excluded bona fide a brain inflammatory pseudotumor, due to the lack of polymorphism, paucity of plasma cells, and fibrosis [12].…”

Inflammatory Pseudotumor in the Lateral Ventricle

“…Only 9 cases of IP in the ventricles have been reported in detail (Table 1), 1,4,5,8,10,11,13,14) occurring in 2 females and 7 males aged 15-73 years (mean 49 years), indicating a tendency to occur in middle-aged or older men. 10) Eight of 9 cases developed in the lateral ventricle, with the remaining case developing in the fourth ventricle.…”

Inflammatory Pseudotumor of the Lateral Ventricle in a Pediatric Patient

“…There are several reported cases of intracranial IP, 13 of which are intraventricular lesions [4,5,6,7,8,9,10,11,12,13,14] (table 1). Only 2 previous cases of intraventricular IP have been reported in pediatric patients and in both instances presented in males with radiographic evidence of biventricular hydrocephalus [4,5].…”