Inflammatory pseudotumor of the bladder in neonates

Abstract

Inflammatory pseudotumors of the bladder are rare in children. We describe a 7-day-old male neonate with inflammatory pseudotumor of the bladder. He presented with a 3-day history of macroscopic hematuria. Ultrasonography, computed tomography and cystoscopy showed an intravesical mass arising from the right lateral wall. Pathologic findings obtained by open excision revealed that the tumor had spindle-shaped cells without significant atypia infiltrating into submucosal fibrous tissue. There has been no evidence of recurrent tumor 12 months post-operatively. To our knowledge our case is the first presentation in a neonate among the reported pediatric cases.

Inflammatory myofibroblastic tumor of the urinary bladder in a 27‐year‐old woman with systemic lupus erythematosus

“…Spindle cell neoplasms are uncommon in the lower genitourinary tract, and may present a difficult differential diagnosis depending on the clinical setting. Although genitourinary IMTs can occur at any age, these patients often present during middle adulthood with isolated hematuria 3–5 . When these tumors arise in other anatomic locations, patients often experience unexplained fever, weight loss, malaise, and anemia, such as described in the presented case.…”

Inflammatory myofibroblastic tumour of the urinary bladder mimicking recurrent uterine carcinosarcoma

“…Inflammatory myofibroblastic tumours (IMTs) are rare benign or locally recurrent soft tissue tumours 1 . The most common sites of origin are the lung, mesentery and omentum.…”

Pseudotumor of the urinary bladder in a child: A case report and review of the literature

“…[3] Inflammatory pseudotumors (IPTs) rarely occur in children, and only one case has been reported in a neonate to date. [4] The pathogenesis of IPT is not clearly known, some have postulated that the lesion develops in response to infection, inflammation, or malignancy, but the causative relationship has not yet been proven. [5] These lesions are locally aggressive with an invasive growth pattern and fail to progress after resection.…”