Inflammatory Pseudotumor of the Nasal Cavity: Successful Management with Corticosteroids

Russell, Matthew S.; Quivey, Jeanne M.; Goldberg, Andrew N.; Bailey, Helen; Glastonbury, Christine M.; Eisele, David W.

doi:10.1002/lary.20433

Cited by 1 publication

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Radiographically, extra-orbital IPT of head and neck region tends to be showing a poorly demarcated lesion with aggressive features that might include bone erosion, sclerosis, remodeling on CT scan. 3 On MRI, the lesions are isointense on T1-weighted image and Hypointense on T2-weighted image. 3 T1-weighted images following gadolinium contrast typically reveals marked enhancement.…”

Section: Introductionmentioning

confidence: 98%

“…1 Mycoplasmata, mycobacteria, Rhodococcus equi, Klebsiella rhinoscleromatis, nocardiae, actinomycetes, Epstein-Barr virus, Herpes simplex 8 have been implicated in pathologic specimens. 2,3 Interleukin 1 contributes to the systemic and local effects of IPT. On pathologic examination there is presence of spindle cells, plasma cells, lymphocytes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Inflammatory pseudotumour of nasal cavity and sinuses: a case report with review of literature

Sharma,

Urangia

2024

Int J Res Med Sci

View full text Add to dashboard Cite

Inflammatory pseudotumor (IPT) is a benign non-neoplastic rare mass lesion clinically and radiologically simulating neoplasm thus generally requiring a biopsy to exclude malignancy. It occurs almost anywhere all over the body with most common locations being lungs and orbit with only 15% of it occurs in head and neck non-orbital region. Here we are described a case of 52-year-old female patient having bleeding from left nostril with swelling, redness of left side of nose and face, initially painless. Radiological imaging was highly suspicious of malignancy. HPE showed inflammatory lesions. The fungal culture report of nasal specimen was showing ‘no growth’. Blood examination was within normal limits; blood sugar levels was within normal limits. Systemic steroids were started which showed drastic improvements. Most of the IPTs in head and neck region shows a benign course, but cases related to paranasal sinuses seems to be of highly aggressive behaviour, with poor response to surgery, chemotherapy, radiotherapy; showing recurrences and fatal outcome. In such cases corticosteroid therapy generally shows good outcome. Tumors for which complete resection would result in morbidity may be treated with corticosteroids conservatively and close follow up. Understanding of natural history and pathophysiologic features of IPTs is helpful in differential diagnosis and may prevent unnecessary surgeries.

show abstract

Section: Introductionmentioning

confidence: 98%