Inflammatory pseudotumor of the spleen: A rare case diagnosed on FNAC

Mundi, Irneet; Singhal, Niti; Punia, Rajpal Singh; Dalal, Usha; Mohan, Harsh

doi:10.1002/dc.21719

Cited by 3 publications

(5 citation statements)

References 44 publications

(62 reference statements)

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“…Two cases of splenic IPT with FNAC findings have been reported previously and showed bland‐looking spindle cell clusters with histiocytes and inflammatory cells . Cytological findings of IPT of other organs, such as the liver and lung, have also been described and, as in our case, showed spindle cells, isolated and in clusters, with mixed inflammatory cells and histiocytes.…”

supporting

confidence: 77%

“…The pathogenesis of splenic IPT is not clearly known, but most authors agree that it is a non‐neoplastic and reactive condition, and should be distinguished from the truly neoplastic inflammatory myofibroblastic tumour, which has similar histology. Inflammatory myofibroblastic tumour can be confirmed by ALK‐1 expression in immunohistochemistry or in cytogenetic study . In our case, ALK‐1 was negative, favouring IPT.…”

supporting

confidence: 52%

“…Dear Editor , Splenic tumours are relatively rare and difficult to diagnose before surgery. Inflammatory pseudotumour (IPT) is a rare space‐occupying lesion of unknown aetiology, characterized by fibroblastic proliferation with varying degrees of inflammatory cell infiltration . Fine needle aspiration cytology (FNAC) is a safe and cost‐effective technique for making a definite pathological diagnosis of splenic lesions .…”

mentioning

confidence: 99%

“…Splenic IPT is usually solitary, well‐defined and discovered incidentally. This tumour is mostly seen in women, often present with fever of unknown origin, and histopathologically is composed of dominant spindle cells admixed with variable numbers of inflammatory cells . Diagnosis of the tumour before surgery is helpful and allows appropriate surgical management.…”

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confidence: 99%

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Fine needle aspiration cytology of inflammatory pseudotumour of the spleen

2014

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woman with pyrexia of unknown origin and a 75year-old man with cardiac tamponade, in whom LE cells were detected in bone marrow aspiration and pericardial fluid samples, respectively; these cases emphasize the importance of a meticulous morphological examination of smears irrespective of gender and age of the patient, even in unusual situations. 7,8 To conclude, although well documented, LE cells in pericardial effusions are extremely rare. Both clinicians and cytopathologists should have a high index of suspicion for SLE in any young woman presenting with an unexplained serous effusion. When numerous, LE cells are easily detectable in body fluid samples, which is of paramount importance in the early management of patients with SLE. Hence, LE cell detection in body fluids is not merely of historical interest, but has an enormous clinical significance.

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confidence: 77%

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confidence: 52%

mentioning

confidence: 99%

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confidence: 99%

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Fine needle aspiration cytology of inflammatory pseudotumour of the spleen

2014

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“…It is formed on the basis of irregular proliferation of inflammatory cells [2] . Generally these tumors have benign behavior with spontaneous regression, but occasionally they have been reported to recur, metastasize and undergo sarcomatous transformation [4] . The clinical symptoms are diverse in nature, with some patients complaining of left flank or abdominal pain, with or without fever and splenomegaly [8] .…”

Section: Discussionmentioning

confidence: 99%

Inflammatory pseudotumor of the spleen

Wayne

2012

JST

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Objective: Inflammatory pseudotumor (ipt) is a rare process which occurs in a number of different organ systems. Methods: This 40 year-old male had no significant past medical history and presented to his primary medical doctor with worsening hypertension. Results: Inflammatory pseudotumor of the spleen (ipt) is a rare disease process which continues to be a challenge to diagnose. Conclusions: Inflammatory pseudotumor (ipt) is a rare process which occurs in a number of different organ systems. The spleen is an unusual location for ipt. Due to non-specific clinical findings at presentation and on radiographic imaging, splenic ipt is challenging to diagnose pre-operatively.

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Inflammatory pseudotumor of the colon causing intussusception: A case report and literature review

Huang

Wang

et al. 2015

WJG

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Inflammatory pseudotumor (IPT) is a rare space-occupying lesion of unknown etiology that can mimic malignancy on clinic-radiological and pathological examination. We describe a rare case of ileocecal intussusception from clinically suspected malignancy of the right colon where the patient underwent right hemicolectomy. Histopathology of the resected specimen confirmed IPT of the colon. This patient was observed to have abnormally elevated total leukocyte count and platelets before and after surgery. In an adult with intussusception associated with an abdominal mass, the possibility of IPT of the colon should be considered. Considering the abnormally high total leukocyte and platelet counts and colonic IPT, it is necessary to prevent postoperative adverse effects due to these changes. Although IPT of the colon is usually a benign process, controversy regarding its management still exists. We consider hemicolectomy as a safe treatment approach for colonic IPT and review the existing literature.

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Inflammatory pseudotumor of the spleen: A rare case diagnosed on FNAC

Cited by 3 publications

References 44 publications

Fine needle aspiration cytology of inflammatory pseudotumour of the spleen

Fine needle aspiration cytology of inflammatory pseudotumour of the spleen

Inflammatory pseudotumor of the spleen

Inflammatory pseudotumor of the colon causing intussusception: A case report and literature review

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