Infliximab-Induced Tubulointerstitial Nephritis with Image Findings of Striated Nephrogram in Crohn’s Disease

Kidney function monitoring in inflammatory bowel disease: The MONITORED consensus

“…Mesalaminerelated nephrotoxicity can be a serious complication and delays in diagnosis and treatment discontinuation can lead to end-stage renal disease [ 6 , 9 , 10 ]. Moreover, nephrotoxicity has also been reported with anti-tumor necrosis factors agents (anti-TNF) and with vedolizumab [11][12][13][14] . Finally, kidney-related extra-intestinal manifestations (EIMs) (e.g., nephrolithiasis, tubulointerstitial nephritis, glomerulonephritis or amyloidosis) can also occur along IBD course independently to the associated treatments [15][16][17] .…”

A riddle wrapped in an enigma: acute kidney injury in a girl with Crohn’s disease: Answers

“…In the present case, ciprofloxacin, NSAIDs, and azathioprine were considered the most likely culprits. Recently, infliximab has also been reported to cause TIN [ 11 , 12 ] and there has been a single report of tramadol as a cause of granulomatous interstitial nephritis [ 13 ].…”