Influence d'un régime hyperlipidique sur la lipogenèse, la mise en réserve et l'utilisation des lipides chez la ratte gestante

Abstract

Summary. Effect of an hyperlipidic diet on lipogenesis and on the storage and mobilization of lipids in the pregnant rat.The aim of the present investigation was to determine the amount of fat accumulated and mobilized during pregnancy in rats fed either an hyperglucidic or an hyperlipidic diet.The feeding of an hyperlipidic diet increased the liver lipid content and did not modify the composition of the mammary gland.Fat was deposited till day 19 of pregnancy ; after that date the fat was mobilized. The increase and decrease of fat stores were independent of the diet consumed. Both were correlated with body changes so that the same linear relationship between the lipid content of the carcass and maternal body weight was observed at all stages of pregnancy.Introduction.

Body fat in pregnant rats at mid- and late-gestation

“…(b) It serves to promote lactation. Decrements in both body fat storage (25) and maternal hypertriglyceridemia (26) occur prior to parturition, coinciding with increments in mammary gland lipoprotein lipase activity (26), both changes driving tissue accumulated fat and circulating triglycerides to the mammary gland for milk synthesis.…”