Influence of a Composite Polylysine-Polydopamine-Quaternary Ammonium Salt Coating on Titanium on Its Ostogenic and Antibacterial Performance

Abstract

Thin oxide layers form easily on the surfaces of titanium (Ti) components, with thicknesses of <100 nm. These layers have excellent corrosion resistance and good biocompatibility. Ti is susceptible to bacterial development on its surface when used as an implant material, which reduces the biocompatibility between the implant and the bone tissue, resulting in reduced osseointegration. In the present study, Ti specimens were surface-negatively ionized using a hot alkali activation method, after which polylysine and polydopamine layers were deposited on them using a layer-by-layer self-assembly method, then a quaternary ammonium salt (QAS) (EPTAC, DEQAS, MPA-N+) was grafted onto the surface of the coating. In all, 17 such composite coatings were prepared. Against Escherichia coli and Staphylococcus aureus, the bacteriostatic rates of the coated specimens were 97.6 ± 2.0% and 98.4 ± 1.0%, respectively. Thus, this composite coating has the potential to increase the osseointegration and antibacterial performance of implantable Ti devices.

The Contribution of the Pore Size of Titanium DC (Direct Current) Sputtered Condensation Polymer Materials to Electromagnetic Interruption and Thermal Properties

“…There are various studies on laser treatment for mechanical stress, the atomic layer deposition of chlorine-containing titanium-zinc oxide nanofilms, 3D-printed titanium lattice structure, titanium alloys, titanium surface modification, porous titanium, and antibacterial applications [1][2][3][4][5][6][7][8][9][10][11][12].…”