Influence of abciximab on evolution of left ventricular function in patients with non-ST-segment elevation acute coronary syndromes undergoing PCI after clopidogrel pretreatment: lessons from the ISAR-REACT 2 trial

Schulz, Stefanie; Mehilli, Julinda; Ndrepepa, Gjin; Dotzer, Franz; Dommasch, Michael; Kufner, Sebastian; Birkmeier, Katrin A.; Tiroch, Klaus; Byrne, Robert A.; Schömig, Albert; Kastrati, Adnan

doi:10.1007/s00392-011-0299-y

Cited by 6 publications

(1 citation statement)

References 49 publications

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“…Применение ингибиторов гликопротеиновых рецепторов IIb/IIIa не привело к снижению риска развития тромботических осложнений и улучшению результатов. В исследованиях ISAR-REACT2 (оценивались пациенты с ОКС без повышения уровня биомаркеров некроза, перенесшие ЧКВ) [6,7] и ISAR-REACT4 (пациентов с ОКСбпST, подвергшихся ЧКВ [8] (абциксимаб + нефракционированный гепарин по сравнению с бивалирудином) было показано, что абциксимаб не улучшал результатов, что косвенно поддерживало целесообразность раннего назначения ингибиторов P2Y 12 .…”

Section: доказательная база преимуществ раннего назначения дат при оксunclassified

Timing of dual antiplatelet therapy in acute coronary syndrome: a problem of coronary artery bypass grafting accessibility for patients

2020

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The feasibility of dual antiplatelet therapy as early as possible in patients with ST-segment elevation acute coronary syndrome, where percutaneous coronary intervention is recommended, has been proven: it improves treatment outcomes by reducing the risk of adverse ischemic events, including stent thrombosis and myocardial infarction.This article provides a detailed analysis of the evidence data and current recommendations on the validity and timing of dual antiplatelet therapy for acute coronary syndrome. The emphasis is made on the controversy regarding the early dual antiplatelet therapy in non-ST-segment elevation acute coronary syndrome. The rationale for using dual antiplatelet therapy only after coronary angiography and determining the revascularization strategy is described, which should increase the accessibility of coronary artery bypass graft surgery for patients.

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Section: доказательная база преимуществ раннего назначения дат при оксunclassified

Timing of dual antiplatelet therapy in acute coronary syndrome: a problem of coronary artery bypass grafting accessibility for patients

2020

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TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention

et al. 2012

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Pre- and early in-hospital procedures in patients with acute coronary syndromes: first results of the “German chest pain unit registry”

et al. 2012

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The establishment of a nation-wide network of certified CPUs optimizes the medical treatment of patients with ACS while providing an ideal infrastructure to evaluate and improve, both on a nation-wide and a single center scale, the adherence to guidelines. The median delay between symptom onset and first medical contact remains high. Although performed relatively rarely, a pre-hospital ECG facilitates earlier diagnosis of a STEMI in a large majority of patients. The introduction of CPUs minimizes in-hospital delays and exploits the benefit of invasive diagnostics and treatment.

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Influence of abciximab on evolution of left ventricular function in patients with non-ST-segment elevation acute coronary syndromes undergoing PCI after clopidogrel pretreatment: lessons from the ISAR-REACT 2 trial

Cited by 6 publications

References 49 publications

Timing of dual antiplatelet therapy in acute coronary syndrome: a problem of coronary artery bypass grafting accessibility for patients

Timing of dual antiplatelet therapy in acute coronary syndrome: a problem of coronary artery bypass grafting accessibility for patients

TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention

Pre- and early in-hospital procedures in patients with acute coronary syndromes: first results of the “German chest pain unit registry”

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