Influence of absorption in linear polarization imaging of melanoma tissues

Li, Dong-Zhi; He, Honghui; Zeng, Nan; Xie, Weidong; Wu, Jian; He, Yonghong; Ma, Hui

doi:10.1142/s1793545814500096

Cited by 6 publications

(6 citation statements)

References 27 publications

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“…The retardance contrast between healthy and obstructed regions of the bladder would be potentially useful to guide augmentation surgeries and monitoring the tissue functionality following tissue engineering therapies . Mueller polarimetry or polarimetric imaging has furthermore been used to investigate muscles , normal and precancerous human cervix , oral and lung tissues , radiofrequency ablated porcine myocardial tissue , skeletal muscle , growth of bacteria colonies , skin including melanoma , animal tissues , bladders , the orientation of collagen fibres in 3‐D space , red blood cell suspensions , etc.…”

Section: The Biomedical Applications Of Mueller‐polarimetric Imagingmentioning

confidence: 99%

Mueller polarimetric imaging for surgical and diagnostic applications: a review

2017

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Polarization is a fundamental property of light and a powerful sensing tool that has been applied to many areas. A Mueller matrix is a complete mathematical description of the polarization characteristics of objects that interact with light, and is known as a transfer function of Stokes vectors which characterise the state of polarization of light. Mueller polarimetric imaging measures Mueller matrices over a field of view and thus allows for visualising the polarization characteristics of the objects. It has emerged as a promising technique in recent years for tissue imaging, improving image contrast and providing a unique perspective to reveal additional information that cannot be resolved by other optical imaging modalities. This review introduces the basis of the Stokes-Mueller formulism, interpretation methods of Mueller matrices into fundamental polarization properties, polarization properties of biological tissues, and considerations in the construction of Mueller polarimetric imaging devices for surgical and diagnostic applications, including primary configurations, optimization procedures, calibration methods as well as the instrument polarization properties of several widelyused biomedical optical devices. The paper also reviews recent progress in Mueller polarimetric endoscopes and fibre Mueller polarimeters, followed by the future outlook in applying the technique to surgery and diagnostics. Tissue polarization properties convey morphological, micro-structural and compositional information of tissue with great potential for label free characterization of tissue pathological changes. Recent progress in tissue polarimetric imaging and polarization resolved endoscopy paved the way for translation of polarimetric imaging to surgery and tissue diagnosis.

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Section: The Biomedical Applications Of Mueller‐polarimetric Imagingmentioning

confidence: 99%

Mueller polarimetric imaging for surgical and diagnostic applications: a review

2017

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“…During calculations, we should first determine this angle according to the spatial orientation of the cylinder and the propagation direction of the photon, and then follow the theory of polarized photon scattering at an infinitely long cylinder, which has been demonstrated in detail in Ref. 13. The scattering coefficient of a microsphere is a constant once its size and refractive index are set.…”

Section: Monte Carlo Simulation and Scbmmentioning

confidence: 99%

“…For the absorption effect in ambient media, Li et al proposed a skin model containing a top isotropic layer, a bottom anisotropic layer, and an absorbing medium to explain the contrast mechanism of polarization imaging for melanoma. 13 Dmitry et al proposed an approximate expression to describe the dependence of the degree of residual linear polarization on the absorption of scattering media. 14 Swami et al studied how the absorption of the scattering medium containing spherical scatterers and absorbing medium affects the depolarization.…”

Section: Introductionmentioning

confidence: 99%

“…16 Mishchenko et al employed the numerically exact superposition T-matrix method to demonstrate that the increasing absorption of particles diminishes and nearly extinguishes certain optical effects such as depolarization and coherent backscattering. 13 Our previous work has developed an optical scattering model called the sphere-cylinder-birefringence model (SCBM) to simulate and simplify complicate and anisotropic biological tissues. 12 Two sets of polarization parameters extracted from the Mueller matrix transformation and Mueller matrix polar decomposition (MMPD) techniques have been used to test this model and explain some pathological changes.…”

Section: Introductionmentioning

confidence: 99%

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Study on the influence of optical absorption on polarization characterization of tissues

et al. 2018

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Absorption effect is a basic optical phenomenon and an important feature in tissue imaging and characterization. Based on our Monte Carlo simulation on the anisotropic tissue model (sphere-cylinder birefringence model), combined with our experiments of tissue phantoms, we demonstrate the influence of absorption effect on Mueller matrix and particularly on depolarization, linear retardance, and diattenuation parameters. The simulation and experimental results show a good consistency on the suppressed depolarization and scatterering induced retardance, and the enhanced diattenuation caused by the absorption, and also indicate the birefringence induced retardance insensitive to the absorption. Study of the phase function of different incident polarized lights and the distribution of scattering number gives a preliminary explanation about the above results. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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“…10 The experimental results on human colon, cervix, and skin cancerous tissues indicated that the backscattering Mueller matrix may serve as a noninvasive tool for cancer diagnosis. [11][12][13] Many tissues contain aligned anisotropic fibrous microstructures, such as the collagen and elastin fibers in epithelial tissues, muscle fibers in cardiac and skeletal muscle tissues. Changes of these fibrous structures can also be characterized by polarization sensitive measurements.…”

Section: Introductionmentioning

confidence: 99%

Mapping local orientation of aligned fibrous scatterers for cancerous tissues using backscattering Mueller matrix imaging

Sun

Zeng

et al. 2014

J. Biomed. Opt

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Abstract. Polarization measurements are sensitive to the microstructure of tissues and can be used to detect pathological changes. Many tissues contain anisotropic fibrous structures. We obtain the local orientation of aligned fibrous scatterers using different groups of the backscattering Mueller matrix elements. Experiments on concentrically well-aligned silk fibers and unstained human papillary thyroid carcinoma tissues show that the m22, m33, m23, and m32 elements have better contrast but higher degeneracy for the extraction of orientation angles. The m12 and m13 elements show lower contrast, but allow us to determine the orientation angle for the fibrous scatterers along all directions. Moreover, Monte Carlo simulations based on the sphere-cylinder scattering model indicate that the oblique incidence of the illumination beam introduces some errors in the orientation angles obtained by both methods. Mapping the local orientation of anisotropic tissues may not only provide information on pathological changes, but can also give new leads to reduce the orientation dependence of polarization measurements. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Influence of absorption in linear polarization imaging of melanoma tissues

Cited by 6 publications

References 27 publications

Mueller polarimetric imaging for surgical and diagnostic applications: a review

Mueller polarimetric imaging for surgical and diagnostic applications: a review

Study on the influence of optical absorption on polarization characterization of tissues

Mapping local orientation of aligned fibrous scatterers for cancerous tissues using backscattering Mueller matrix imaging

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