Influence of Age and Education on the Performance of Elderly in the Brazilian Version of the Montreal Cognitive Assessment Battery

Pinto, Tiago Coimbra Costa; Machado, Leonardo; Bulgacov, Tatiana M; Rodrigues-Júnior, Antônio Luiz; Costa, María Lúcia Gurgel da; Ximenes, Rosana Christine Cavalcanti; Sougey, Éverton Botelho

doi:10.1159/000489774

Cited by 27 publications

(23 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the current study we replicated the approach applied for the MMSE [31]. Scores of the MoCA may be also influenced by age or education [8, 10-13, 16, 32-33]. Therefore, norms should be adjusted to these factors.…”

Section: Introductionmentioning

confidence: 71%

See 1 more Smart Citation

Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons

Bartoš

Fayette

2018

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

Background: The Czech version of the Montreal Cognitive Assessment (MoCA-CZ) and delayed recall of 5 words have not been validated in patients with mild cognitive impairment (MCI) due to Alzheimer disease (AD) and compared to norms of a large population. Method: The MoCA-CZ was administered to 1,600 elderly individuals in 2 groups consisting of 48 patients with MCI due to AD (AD-MCI) and 1,552 normal elderly adults. Results: MoCA-CZ scores were significantly lower in the AD-MCI patients than in the normal elderly (21 ± 4 vs. 26 ± 3 points; p = 0.03). Under the recommended cutoff score of ≤25, the MoCA-CZ demonstrated an excellent sensitivity of 94% but a low specificity of 62%. When the score was reduced to ≤24, the MoCA-CZ showed an optimal sensitivity of 87% for AD-MCI and a specificity of 72%. Normal elderly persons should recall at least 2 words after delay (sensitivity 80%, specificity 74%). Several cutoff points were derived from normative data stratified by age and education. Conclusions: The cutoff for AD-MCI and stratified norms are available for the MoCA total score and delayed recall of the Czech version. The cut-off scores of the MoCA-CZ, sensitivity, and specificity are lower than in the original study.

show abstract

Section: Introductionmentioning

confidence: 71%

“…The test scores on the MoCA range from 0 to 30 points. The result is correctly interpreted when normative data and cutoffs are available for targeted populations [9-13]. …”

Section: Introductionmentioning

confidence: 99%

Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons

Bartoš

Fayette

2018

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

show abstract

“…Education is considered a criterion for the establishment of normative data for cognitive tests, and the impact the level of education has on cognitive performance has been well established in the literature [5, 7, 8, 9, 10, 11, 12, 13, 14, 15]. Furthermore, the author of the MoCA proposed adding 1 point to individuals with 12 years of education or less, aiming to correct the effect education has on MoCA performance [3].…”

Section: Introductionmentioning

confidence: 99%

Optimal Cutoff Scores for Dementia and Mild Cognitive Impairment in the Brazilian Version of the Montreal Cognitive Assessment among the Elderly

Pinto

Santos

Machado

et al. 2019

Dement Geriatr Cogn Disord Extra

Self Cite

View full text Add to dashboard Cite

Objective: To propose cutoff scores for the Brazilian version of the Montreal Cognitive Assessment (MoCA-BR) stratified by education in order to detect mild cognitive impairment (MCI) and mild Alzheimer’s disease (AD) in the elderly. Method: A transversal study in health centers was performed on 159 elderly people with 4–12 years of education and 70 of their peers with over 12 years of schooling. The MoCA-BR cutoff scores for screening cognitive impairment were determined based on an ROC curve analysis. Results: The ROC curve analysis indicated that cutoff scores under 20 were good for screening elderly people with cognitive impairment with more than 12 years of education, and scores under 21 were good for screening those with 4–12 years of education. Conclusions: MoCA-BR scores under 21 points (after adding 1 point to the elderly with ≤12 years of education) indicate a need to continue the diagnostic investigation with regular follow-ups.

show abstract

“…We assumed that the power (1-β) was 80%, ɑ was 0.05 and the rate of loss to follow-up was 20%. Due to the lack of statistical data on SCD, we calculated the sample size with data reported by Licher et al 30 and Pinto et al 31 (HR=1.03, SD=8.2, R²=0.127) from cognitively normal elderly subjects for the association between age and cognitive decline. This calculation rendered a total sample size of 762.…”

Section: Methodsmentioning

confidence: 99%

Sino Longitudinal Study on Cognitive Decline (SILCODE): protocol for a Chinese longitudinal observational study to develop risk prediction models of conversion to mild cognitive impairment in individuals with subjective cognitive decline

Wang

et al. 2019

BMJ Open

View full text Add to dashboard Cite

IntroductionUnderstanding the biological mechanism of subjective cognitive decline (SCD) in preclinical Alzheimer’s disease (AD) and identifying those who will soon convert to mild cognitive impairment (MCI) are critical for developing appropriate strategies for early diagnosis and intervention of AD. We present the study protocol of the Sino Longitudinal Study on Cognitive Decline (SILCODE), a longitudinal observational study focusing on SCD in the context of AD.Methods and analysisWithin SILCODE, approximately 800 subjects with SCD who are between 50 and 79 years old will be recruited through standardised public advertisements or memory clinics. They will undergo extensive assessment, including clinical and neuropsychological assessments, blood sample collection for plasma beta-amyloid and ApoE genotype, urine samples collection for AD7c-NTP, and multimodal MRI scans (structural MRI, diffusion tensor imaging, resting-state functional MRI and optional task-based functional MRI) as well as optional glucose metabolism and amyloid positron emission tomography. Subjects will be contacted by telephone every 3 months and interviewed, on average, every 15 months for 5 years. The study endpoint is the development of mild cognitive impairment or dementia. Jak & Bondi’s actuarial neuropsychological method will be used for diagnosis of MCI. The least absolute shrinkage and selection operator logistic regression model followed by the sub-distribution hazard function model with death as a competing risk will be constructed to establish risk prediction models.Ethics and disseminationThe ethics committee of the Xuanwu Hospital of Capital Medical University has approved this study protocol (ID: [2017]046). The results will be published in peer-reviewed journals and presented at national and international scientific conferences.Trial registration numberNCT03370744; Pre-results.

show abstract

Influence of Age and Education on the Performance of Elderly in the Brazilian Version of the Montreal Cognitive Assessment Battery

Cited by 27 publications

References 15 publications

Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons

Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons

Optimal Cutoff Scores for Dementia and Mild Cognitive Impairment in the Brazilian Version of the Montreal Cognitive Assessment among the Elderly

Sino Longitudinal Study on Cognitive Decline (SILCODE): protocol for a Chinese longitudinal observational study to develop risk prediction models of conversion to mild cognitive impairment in individuals with subjective cognitive decline

Contact Info

Product

Resources

About