Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa

Akpa, Onoja Matthew; Ovbiagele, Bruce; Akpalu, Albert; Wahab, Kolawole; Komolafe, Morenikeji; Obiako, Reginald; Owolabi, Lukman; Osaigbovo, Godwin; Jenkins, Carolyn; Ogbole, Godwin; Fakunle, Adekunle; Tiwari, Hemant K.; Arulogun, Oyedunni; Arnett, Donna K.; Asowata, Osahon Jeffery; Akinyemi, Rufus; Owolabi, Mayowa

doi:10.1016/j.jns.2021.117573

Cited by 6 publications

(3 citation statements)

References 29 publications

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“…In general, HTN in KSA is at high risk in males and those at younger ages ( Buang et al, 2019 ; Dar et al, 2019 ). And as HTN may sharply increase with age and other combinations of cardio-metabolic risk factors ( Sarfo et al, 2021 ), more attention should be paid to all community members with specific consideration to those at higher risk. The level of awareness about HTN, for instance, is needed for all community members.…”

Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

et al. 2023

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Introduction Stroke is a significant health problem and is considered one of the leading causes of mortality and permanent disability worldwide. Hypertension is a primary risk factor for stroke. Thus, hypertensive patients’ knowledge, attitudes, and practices (KAP) are essential in preventing stroke. Objective To examine hypertensive patients’ KAP towards stroke prevention among rural population in Saudi Arabia. Methods The study utilized a cross-sectional design. The data were collected using a convenience sampling technique from hypertensive patients in the northwestern rural areas of Riyadh Province. A self-administered questionnaire was adapted from the Stroke Recognition Questionnaire (SRQ) and utilized to assess KAP towards stroke prevention among rural hypertensive patients. The STrengthening of the Reporting of OBservational studies in Epidemiology (STROBE) checklist was used to report the study. Results A total of 196 hypertensive patients participated in the study. The total mean scores categorization into three quartiles showed that most respondents had poor levels of KAP towards stroke prevention. Weak positive correlations were found between KAP of patients. There were statistically significant differences between respondents’ attitudes and practices with their age, education, marital status, and occupational status. Discussion This study denoted poor levels of KAP towards stroke prevention among hypertensive patients living in rural areas. This study showed the importance of further considering rural population by which improving their health and quality of life. Extending health educational programs and behavior-changing strategies to rural areas is essential to increase hypertensive patients and general public awareness about their stroke prevention and other health-related concerns.

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Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

et al. 2023

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“…The study conducted by Sarfo et al . 20 indicated that CVD has a high prevalence rate related to age and that senile patients have a significantly higher risk of stroke than younger patients. Older age is also an independent risk factor for the incidence of PND 21 , and these two risk factors (age and CVD) may synergistically lead to its incidence.…”

Section: Discussionmentioning

confidence: 99%

Association between cerebrovascular disease and perioperative neurocognitive disorders: a retrospective cohort study

Feng,

Liu,

et al. 2023

International Journal of Surgery

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Background: Previous studies have shown that patients with cerebrovascular disease (CVD) have a significantly increased risk of cognitive decline or dementia; however, the association between preoperative CVD and perioperative neurocognitive disorders (PNDs) remains unclear. This study aimed to explore the correlation between preoperative CVD and PNDs, as well as combine logistic regression and ROC curves to construct a clinical prediction PND model. Materials and Methods: This retrospective cohort study evaluated 13,899 surgical patients of a large-scale comprehensive hospital between January 2021 and January 2022 to explore the association between preoperative CVD and PNDs, with follow-up to monitor postoperative survival until February 28, 2023, unless the patient died. The study participants comprised all inpatients from the Bone and Joint Surgery, Spine Surgery, Urology, Hepatobiliary Surgery, Gastrointestinal Surgery, and Thoracic Surgery departments. Patients were classified into two groups: the CVD group with a confirmed diagnosis and the non-cerebrovascular disease (NCVD) group. The incidence of PNDs was measured, and potential associations between patient demographic information, preoperative comorbidities, and CVD, as well as the correlation between preoperative CVD and PNDs, were investigated by multivariate logistic regression analysis. Next, we constructed a clinical prediction PND model by drawing the receiver operating characteristic (ROC) curve. The postoperative survival of all patients was tracked, and a survival curve was constructed and incorporated into the Cox proportional hazard regression model to analyze the relationship between preoperative CVD and overall postoperative survival rate. Results: Of the included 13,899 patients, propensity score matching yielded 1006 patient pairs. Multivariate logistic regression analysis revealed that CVD was an independent risk factor for PNDs [Odds ratio: 10.193; 95% confidence interval: 7.454–13.938; P<0.001]. Subsequently, we developed a clinical prediction model for PNDs by multivariate logistic regression analysis. The area under the ROC curve was 0.798 (95% CI: 0.765–0.830). The survival of 11,702 patients was followed up. Multivariate Cox hazard ratio regression analysis revealed that CVD affected the overall postoperative survival rate (Hazard ratio, 1.398; 95% confidence interval: 1.112–1.758; P＜0.001). Conclusion: CVD was an independent risk factor for PNDs and affected the overall postoperative survival rate of surgical patients with preoperative CVD.

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“…Low-and-Middle Income Countries (LMICs) in sub-Saharan Africa now have the greatest burden of stroke with incidence rates of 316 per 100,000, prevalence of 14.6 per 1000 and a 5-year mortality rate of up to 40% [4][5][6][7][8][9]. Because stroke affects a predominantly young to middle age population in SSA [10][11][12], the trajectory of stroke survivors on the continent is projected to rise, requiring proper planning and allocation of resources to deal with this imminent public health challenge.…”

Section: Introductionmentioning

confidence: 99%

Nationwide rates of outpatient clinic attendance by stroke survivors in Ghana: Analysis by region and facility

Commeh

Tandoh

Agbogbatey

et al. 2022

Journal of the Neurological Sciences

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Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa

Cited by 6 publications

References 29 publications

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

Knowledge, Attitudes, and Practices of Hypertensive Patients Towards Stroke Prevention Among Rural Population in Saudi Arabia: A Cross-Sectional Study

Association between cerebrovascular disease and perioperative neurocognitive disorders: a retrospective cohort study

Nationwide rates of outpatient clinic attendance by stroke survivors in Ghana: Analysis by region and facility

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