1999
DOI: 10.1016/s0022-3468(99)90308-1
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Influence of age on the presentation and outcome of choledochal cyst

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Cited by 77 publications
(70 citation statements)
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“…The incidence of cholangitis in patients with Caroli's disease can reach 60% 21 . Although there are few reports on the microscopic abnormalities of the liver of patients with choledochal cyst, some studies claim that most patients, even those with prenatal diagnosis or operated in the first year of life, have changes in their liver biopsies as a result of biliary obstruction, with ductular proliferation, fibrosis and even cirrhosis [22][23][24] , agreeing with our results, since only two liver histopathology exams were normal. Not even the patients treated before one year of age showed normal liver histology.…”
Section: Results Results Results Resultssupporting
confidence: 90%
“…The incidence of cholangitis in patients with Caroli's disease can reach 60% 21 . Although there are few reports on the microscopic abnormalities of the liver of patients with choledochal cyst, some studies claim that most patients, even those with prenatal diagnosis or operated in the first year of life, have changes in their liver biopsies as a result of biliary obstruction, with ductular proliferation, fibrosis and even cirrhosis [22][23][24] , agreeing with our results, since only two liver histopathology exams were normal. Not even the patients treated before one year of age showed normal liver histology.…”
Section: Results Results Results Resultssupporting
confidence: 90%
“…5 The primary differential consideration is BA with a cyst (Japanese type I cyst). [6][7][8] This is a critical differential because of the different surgical implications. Patients with BA type I cyst have a very high incidence of hepatic fibrosis.…”
Section: Denouement and Discussionmentioning
confidence: 99%
“…7 Neonatal biliary choledochal cysts even without atresia (those discovered in patients younger than 4 months) have been reported to develop hepatic fibrosis, making early surgical intervention warranted to prevent progression. 6 Figure 2 Intraoperative cystography. Contrast injected into the porta hepatis cyst flows into the slightly dilated intrahepatic biliary tree and into the duodenum and jejunum (black arrow).…”
Section: Denouement and Discussionmentioning
confidence: 99%
“…Los quistes de colédoco intra hepáticos pertenecen a desórdenes fibropoliquísticos por probables malformaciones de la placa ductal, mientras que los quistes extrahepáticos se asocian a anomalías en el conducto bilio-pancreático en el 92% de los pacientes 2 , por lo que se piensa que el aumento del reflujo de jugo pancreático dentro del árbol biliar, lleva a la exposición de la pared del conducto común a las enzimas pancreáticas y a un aumento de presión en el colédoco, lo cual resulta en la formación de quistes 4 . Sólo un 20% de los pacientes afectados desarrolla la tríada clásica de ictericia, dolor abdominal y masa en hipocondrio derecho, mientras que la mayoría, presenta alguno de estos síntomas de forma aislada 5 . El objetivo del presente estudio ha sido analizar aquellas variables introducidas por servicio de cirugía pediátrica de nuestro centro, para la optimización en el diagnóstico y tratamiento del quiste de colédoco, basándonos en la revisión de la literatura y en nuestra propia experiencia durante los últimos 24 años.…”
Section: Optimización En La Estrategia Diagnóstica Y Terapéutica En Eunclassified