Influence of Aging on Systolic Left Ventricular Wall Motion Velocities Along the Long and Short Axes in Clinically Normal Patients Determined by Pulsed Tissue Doppler Imaging

Onose, Yukiko; Oki, Takashi; Mishiro, Yuichiro; Yamada, Hirotsugu; Abe, Miho; Manabe, Kazuyo; Kageji, Yoshimi; Tabata, Tomotsugu; Wakatsuki, Tetsuzo; Ito, Susumu

doi:10.1016/s0894-7317(99)70144-6

Cited by 75 publications

(60 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The increase in Sw1 along the long axis contributes to spherical changes in the LV cavity during isovolumic contraction phase [23], and therefore a decrease in this peak velocity can be useful in the early diagnosis of impaired contractility in elderly individuals with normal LV pump function [24,25]. With respect to the TDI findings during early systole, Zamorano et al [26] simultaneously recorded M-mode color TDI and LV-aortic-left atrial pressures, and reported that there was a good correlation between the time interval assessed hemodynamically and that based on the velocity interface obtained with M-mode color TDI during the isovolumic contraction phase.…”

Section: Systolic Functionmentioning

confidence: 99%

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Oki

2003

J Echocardiogr

Self Cite

View full text Add to dashboard Cite

In general, pump function and myocardial contractility should be assessed when evaluating left ventricular (LV) systolic function. Ejection fraction obtained from left ventriculography is routinely used as an index of pump function, and the maximum value of the first derivative of LV pressure curve (peak dP/dt) has been used as an index of myocardial contractility. On the other hand, active relaxation of the LV myocardium during early diastole and LV passive filling or compliance during mid-to late diastole are important factors in evaluating LV diastolic function. To obtain this information, the time constant of the LV pressure decay during isovolumic diastole (tau) and LV end-diastolic pressure, which are calculated from the LV pressure curve recorded during cardiac catheterization, is used. However, invasive hemodynamic measurements cannot be performed in all patients, nor are they appropriate for follow-up evaluation involving repeated examinations.Recently, routine echocardiography has facilitated the noninvasive evaluation of LV systolic and diastolic function. The percent fractional shortening of the LV based on M-mode echocardiography and the LV ejection fraction determined by two-dimensional echocardiography are indices of LV pump function, and therefore cannot accurately evaluate LV myocardial contractility. On the other hand, "diastology" has become an important clinical topic [1]. There are several reasons why assessment of diastolic function is important: 1) 30 to 40% of patients evaluated for congestive heart failure have normal LV pump function [2,3]; 2) the transmitral flow velocity pattern, which is recorded using the pulsed Doppler method, may be an index for noninvasive evaluation of LV diastolic function [4]; and 3) the prognosis is poor in patients with LV systolic dysfunction and pseudonormalization or restrictive pattern of the transmitral flow velocity [5,6]. However, it has been shown that the diastolic indices obtained from transmitral and pulmonary venous flow velocities are influenced by loading conditions, especially by the pre- The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left AbstractThe widespread use of the pulsed Doppler echocardiography has facilitated the noninvasive evaluation of hemodynamic abnormalities of the left atrium and left ventricle (LV) based on transmitral and pulmonary venous flow velocity patterns. However, it has been shown that loading conditions, especially preload, influence the indices obtained from these velocity patterns. Recently, tissue Doppler imaging (TDI) has been applied to the clinical setting to assess LV myocardial function. In particular, this procedure has the following characteristics: 1) it can provide circumferential and longitudinal information for the LV myocardium; 2) the early diastolic LV myocardial parameters determined by TDI are not influenced by preload; 3) LV myocardial contractility can be evaluated from the early systolic parameters; 4) LV systolic and diastolic asynchrony can be detected; 5) myoca...

show abstract

Section: Systolic Functionmentioning

confidence: 99%

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Oki

2003

J Echocardiogr

Self Cite

View full text Add to dashboard Cite

show abstract

“…These parameters describe systolic and diastolic myocardial function in three mutually perpendicular planes 21,22 . speckle tracking echocardiography imaging may be used for early detection of regional systolic and diastolic lV dysfunction 8,23,24 in patients with preserved lVeF and cardiovascular risk factors.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal, circumferential and radial systolic left ventricular function in patients with heart failure and preserved ejection fraction

Gregorová¹,

Meluzı́n²,

Štěpánová³

et al. 2016

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

Introduction. Heart failure with preserved left ventricular ejection fraction (HFPEF) is an epidemiologically serious disease. Noninvasive diagnosis of HFPEF remains challenging. The current diagnosis is based on evidence of diastolic dysfunction, albeit systolic dysfunction is also present but not included in the diagnostic algorithm. The aim of this study was to analyze the longitudinal (long), circumferential (circ) and radial (rad) component of systolic left ventricular (LV) function in patients with exertional dyspnea of unexplained etiology and normal left ventricular ejection fraction (LVEF). Methods. One hundred and twenty-two patients with exertional dyspnea of unexplained etiology and normal LVEF and 21 healthy controls, underwent echocardiography examination at rest and at the end of symptom-limited exercise. We analysed the longitudinal, circumferential and radial deformation of myocardium using two dimensional speckle tracking echocardiography in all subjects. Results. Patients with exertional dyspnea and preserved LVEF were divided into group A1 (46 patients meeting the criteria for the diagnosis HFPEF) and group A2 (76 patients without HFPEF). Group A1 had significantly worse longitudinal and circumferential systolic LV function than group A2. Subjects in group A1 compared to group A2 showed significantly different strain rates during atrial contraction (SR A), circ and ratio of peak early trans-mitral flow velocity (E) and strain rate E wave (E / SR E) circ. Multivariate logistic regression analysis showed that the SR parameter A circ is an independent predictor of HFPEF (odds ratio 0.550, 95% confidence interval: 0.370 -0.817, P value 0.003). Conclusion. Longitudinal and circumferential LV deformation was significantly more impaired in patients with HFPEF than in patients with exertional dyspnea without HFPEF. In patients with exertional dyspnea and normal LVEF, the value of SRA circ appears to be a significant and independent predictor of HFPEF. This parameter may, in the future complement the diagnostic algorithm for HFPEF.

show abstract

“…However, the longitudinal myocardial contractility in early systole is impaired with increased age, even in healthy individuals [16]. Recently, Sun et al [17] demonstrated that the myocardial velocities and strain rate showed a significant dependence on age, whereas displacement and peak systolic strain measures were less affected.…”

Section: Discussionmentioning

confidence: 99%

Regional Myocardial Systolic Function Assessed by Strain Tissue Doppler Imaging in Patients With Isolated Noncompaction of Left Ventricular Myocardium: A Study of Two Cases

et al. 2005

Self Cite

View full text Add to dashboard Cite

Noncompacted myocardium has been previously described as the presence of persistent intramyocardial sinusoids. However, the latter is associated with congenital obstructive lesions of the left or right ventricular outflow tract, such as pulmonary atresia with intact ventricular septum [1]. In such patients, regression of the embryogenic sinusoid is impaired during ontogenesis by ventricular pressure overload, resulting in deep recesses that communicate with both the ventricular cavity and the coronary artery system [2,3].By contrast, isolated noncompaction of the left ventricular myocardium (INVM) is an idiopathic cardiomyopathy characterized by an altered structure of the myocardial wall as a result of intrauterine arrest of compaction of the myocardial fibers in the absence of any coexisting congenital lesion [4]. There is continuity between the left ventricular (LV) cavity and the deep intertrabecular recesses that are filled with blood from the ventricular cavity without evidence of communication to the epicardial coronary artery system [5,6]. AbstractIsolated noncompaction of the left ventricular myocardium (INVM) is associated with a high incidence of heart failure.However, it is difficult to determine accurately left ventricular (LV) systolic function because of the trabeculated ventricles. The purpose of this study was to clarify whether strain imaging could detect regional myocardial systolic function in 2 patients with INVM. We recorded myocardial strain profiles at the basal, mid-, and apical portions of the LV free wall and ventricular septum (VS) in the apical LV long-axis view. Case 1 (15-year-old male) was referred to our hospital because of ECG abnormalities. Case 2 (83-year-old female) was admitted to our hospital for congestive heart failure.Two-dimensional echocardiography in both patients showed numerous prominent trabeculations and deep intertrabecular recesses at the apex of the LV wall. Because of the trabeculations, it was difficult to determine accurately LV ejection fraction by 2-dimensional echocardiography. The percent fractional shortening of the LV (%FS) in both cases was within a normal range. However, the peak systolic strains at the apical, mid-, and basal portions of the LV free wall were lower in Case 2 (-12, -12, and -11%, respectively) than in Case 1 (-33, -37, and -37%, respectively). The peak systolic strains at the apical, mid-, and basal portions of the VS were also lower in Case 2 (-11, -16, and -11%, respectively) than in Case 1 (-27, -27, and -29%, respectively). We conclude that strain measurements are useful for evaluating regional myocardial systolic function in patients with INVM. (J Echocardiogr 2005; 3: 40-45) Key words: isolated noncompaction of the left ventricular myocardium, strain imaging, regional myocardial systolic function

show abstract

Influence of Aging on Systolic Left Ventricular Wall Motion Velocities Along the Long and Short Axes in Clinically Normal Patients Determined by Pulsed Tissue Doppler Imaging

Cited by 75 publications

References 26 publications

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Longitudinal, circumferential and radial systolic left ventricular function in patients with heart failure and preserved ejection fraction

Regional Myocardial Systolic Function Assessed by Strain Tissue Doppler Imaging in Patients With Isolated Noncompaction of Left Ventricular Myocardium: A Study of Two Cases

Contact Info

Product

Resources

About