Influence of Amino Acids in Dairy Products on Glucose Homeostasis: The Clinical Evidence

Chartrand, Dominic; Silva, Marine S. Da; Julien, Pierre; Rudkowska, Iwona

doi:10.1016/j.jcjd.2016.10.009

Cited by 39 publications

(28 citation statements)

References 53 publications

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“… 35 Dairy protein and major dairy amino acids have also induced beneficial metabolic effects in trials, such as lowered blood pressure and improved glycemic control. 11 , 36 – 38 Interestingly, though a meta-analysis observed an increased risk of all-cause mortality with high dairy intakes (>750 mL/d), 39 indicating that high intakes may not be favorable. Accordingly, we observed higher HF risk mainly among those with the highest intake of total (>927 g/d) and fermented dairy (>281 g/d).…”

Section: Discussionmentioning

confidence: 99%

Intake of Different Dietary Proteins and Risk of Heart Failure in Men

Virtanen

Voutilainen

Koskinen

et al. 2018

Circ: Heart Failure

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Section: Discussionmentioning

confidence: 99%

Intake of Different Dietary Proteins and Risk of Heart Failure in Men

Virtanen

Voutilainen

Koskinen

et al. 2018

Circ: Heart Failure

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“…Milk proteins exerted the strongest influence on the secretion of insulin and incretins compared to other animal proteins [7]. It is mostly attributed to the high content of branched-chain amino acids (leucines, isoleucines, valines) which activate various pathways associated with insulin resistance [8]. However, apart from protein components, such as insulinogenic amino acids and bioactive peptides, dairy products also contain calcium, magnesium, potassium and carbohydrates with low glycemic index, which all seem to have a favorable effect on the control of glycemia, insulin secretion, insulin sensitivity of tissues and the reduction in the risk of T2DM.…”

Section: Dairy Products and Insulin Resistancementioning

confidence: 99%

Milk and Dairy Products and Their Impact on Carbohydrate Metabolism and Fertility—A Potential Role in the Diet of Women with Polycystic Ovary Syndrome

2020

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Milk and dairy products are considered an important component of healthy and balanced diet and are deemed to exert a positive effect on human health. They appear to play a role in the prevention and treatment of carbohydrate balance disturbances. The products include numerous valuable components with a potential hypoglycemic activity, such as calcium, vitamin D, magnesium and probiotics. Multiple authors suggested that the consumption of dairy products was negatively associated with the risk of type 2 diabetes mellitus, insulin resistance and ovulation disorders. However, there are still numerous ambiguities concerning both the presumed protective role of dairy products in carbohydrate metabolism disorders, and the advantage of consuming low-fat dairy products over high-fat ones, especially in women with the risk of ovulation disorders. Therefore, this literature review aims at the presentation of the current state of knowledge concerning the relationship between dairy product consumption and the risk of insulin resistance, type 2 diabetes mellitus in women, and the potential effect on the course of polycystic ovary syndrome.

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“…Dairy products are complex foods containing specific nutrients that could have beneficial effects on T2D risk factors. Among these nutrients, BCAAs contained in whey protein in dairy products are known to stimulate insulin secretion (9). Further, the dairy matrix contains significant amounts of calcium and vitamin D and a small amount of unique ruminant trans FAs, which have been associated with reduced insulin resistance and improved insulin sensitivity (10,11).…”

Section: Introductionmentioning

confidence: 99%

Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

O’Connor

Turcotte

Gagnon

et al. 2019

Advances in Nutrition

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Dairy product intake is inversely associated with the risk of type 2 diabetes (T2D) in numerous cohort studies; yet, the beneficial effects of increased dairy product intake on T2D risk factors such as fasting plasma glucose, fasting insulin, insulin resistance with the homeostasis model assessment, and glycated hemoglobin (HbA1c) remain inconclusive in clinical trials. The objective of this study was to systematically review clinical trials observing the effects of elevated compared with minimal intake of dairy products on T2D risk factors in subjects without diabetes. Five databases [Medline, EMBASE, Central, CINAHL, AMED (Allied and Complementary Medicine)] were searched to identify randomized controlled trials that used elevated quantities of dairy products from ruminant sources in comparison with a lower intake in control groups. The review outcomes were fasting blood glucose, fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and HbA1c. Risk of bias and quality of evidence according to Grading of Recommendations Assessment, Development, and Evaluation were addressed. From the 10,627 citations screened, 44 studies (3016 participants) were included, 38 of which were used in the meta-analyses. Fasting glucose was positively associated with elevated dairy intake [34 studies, n = 2678; mean difference (MD): 0.

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Influence of Amino Acids in Dairy Products on Glucose Homeostasis: The Clinical Evidence

Cited by 39 publications

References 53 publications

Intake of Different Dietary Proteins and Risk of Heart Failure in Men

Intake of Different Dietary Proteins and Risk of Heart Failure in Men

Milk and Dairy Products and Their Impact on Carbohydrate Metabolism and Fertility—A Potential Role in the Diet of Women with Polycystic Ovary Syndrome

Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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