Influence of amla fruits (Emblica officinalis) on the bio-availability of iron from staple cereals and pulses

Gowri, Bindiganavale Srihari; Platel, Kalpana; Prakash, Jamuna; Srinivasan, Krishnapura

doi:10.1016/s0271-5317(01)00362-1

Cited by 28 publications

(16 citation statements)

References 8 publications

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“…[313233] Presence of ascorbic acid (vitamin C) in Amalaki has a significant effect on iron bioavailability from cereals and pulses in vitro . [34] Lauha Bhasma also has a significant hematinic and cytoprotective activity,[35] hemoglobin regeneration efficacy. [36]…”

Section: Methodsmentioning

confidence: 99%

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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Background:Anemia in pregnancy is multi-factorial. Iron deficiency anemia (IDA) is the most common one. Major cause is increased demand of iron during pregnancy. In Ayurveda, under Pandu-Roga the features of anemia are described. It is characterized by Vaivarnyata or Varnanasha (change/destruction in normal color of the body), a disorder of Pitta vitiation. Ayurvedic management is an effective way of curing anemia in general by a large number of Lauha preparations of which Dhatrilauha has been used widely for centuries.Aim:To evaluate the effect of Dhatrilauha in the management of IDA based on the scientific parameters among pregnant patients.Materials and Methods:A total of 58 cases were selected by simple randomized sampling method as per inclusion criteria of pregnant women between 4th and 7th months of pregnancy with a clinical diagnosis and laboratory confirmation of IDA. Dhatrilauha 500 mg in two divided doses after food with normal potable water were given for 45 days with three follow-ups, each of 15 days intervals. Final assessment was done after completion of 45 days and results were statistically analyzed by using Cochran's Q-test and Student's t-test.Results:Dhatrilauha showed statistically significant (P < 0.01) improvement in the majority of sign-symptoms and objective parameters such as weakness, fatigue, palpitation, effort intolerance, breathlessness, heartburn, pallor, constipation, hemoglobin, red blood cells (RBC), hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, RBC distribution width, mean platelet volume, serum iron, and total iron binding capacity.Conclusion:Dhatrilauha possesses many fold effectiveness in anemia (IDA), which was evidenced with the significant results obtained in the majority of parameters in this study.

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Section: Methodsmentioning

confidence: 99%

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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“…The reduction of iron by AA has been suggested to increase dietary absorption of non-heme iron [42,43]. Vitamin C rich fruits such as goose berry has been reported to increase the bioavailability of iron from staple cereals and pulses [44]. Recent observations are of the view that vitamin C inhibits the expression of hepcidin and by affecting erythropoietin receptor in HepG2 cells and the bioavailability of iron provides protection against anaemia due to iron deficiency [45].…”

Section: Vitamin C and Ironmentioning

confidence: 99%

Vitamin C in Disease Prevention and Cure: An Overview

et al. 2013

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The recognition of vitamin C is associated with a history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radical damage. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. However the significance and beneficial effect of vitamin C in respect to human disease such as cancer, atherosclerosis, diabetes, neurodegenerative disease and metal toxicity however remains equivocal. Thus further continuous uninterrupted efforts may open new vistas to understand its significance in disease management.

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“…This finding was in close agreement with the results obtained by ref. [49], where addition of aonla at a level of 10 per cent to cooked finger millet samples did not show any significant effect on in-vitro iron bioavailability under simulated gastrointestinal conditions. This behaviour may be attributed to the inability of ascorbic acid to overcome the inhibitory effect of phytic acid and tannin content present in finger millet and aonla.…”

Section: Figure 2 Effect Of Fortificant and Addition Of Aonla Powdermentioning

confidence: 82%

Iron Bioavailability, Storability and Sensory Evaluation of Iron Fortified Extruded Snacks Intended to Alleviate Iron Deficiency in Indian Children

Gaur

Visvanathan²

2015

IJNFS

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Abstract:Iron deficiency is one of the major health problems in India and is significantly affecting the growth and development of children. The mid day meals offered as an intervention to improve nutritional standards could not fulfill daily iron requirements of children. Iron fortified snack products were developed to supplement these daily meals, by extrusion cooking of nutritional orphan crop finger millet added with fortifying agents NaFeEDTA (sodium iron ethylenediaminetetraacetate) or ferrous fumarate and aonla (Emblica officinalis Gaertn); as a source of ascorbic acid. The extrusion variables were optimized at moisture 18%, barrel temperature 115°C, screw speed 260 rpm and addition of cassava at the rate of 30 %, based on the expansion ratio. Iron bioavailability from products was assessed in terms of Haemoglobin Maintenance Efficiency (HME) through Haemoglobin regeneration assay in chicks. Overall HME was significantly different (p < 0.05) for feed fortified with ferrous fumarate (28.66 %), feed fortified with NaFeEDTA (35.26 %), and feed without fortificant (19.15%). Addition of aonla powder to chick feed significantly improved the HME in case of ferrous fumarate whereas, showed no significant effect in the case of NaFeEDTA and feeds without fortificant. Storage stability was evaluated on the basis of density, hardness, and sensory characteristics for both fresh and stored samples. Samples were fried, dusted with spice mix and were packed for storage studies in low-density polyethylene (LDPE) and aluminium foil packaging material, with or without nitrogen flushing. In conclusion, products fortified with NaFeEDTA and packed in aluminium foil with nitrogen flushing were found optimal in terms of iron bioavailability, storability and consumer acceptability.

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Influence of amla fruits (Emblica officinalis) on the bio-availability of iron from staple cereals and pulses

Cited by 28 publications

References 8 publications

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Vitamin C in Disease Prevention and Cure: An Overview

Iron Bioavailability, Storability and Sensory Evaluation of Iron Fortified Extruded Snacks Intended to Alleviate Iron Deficiency in Indian Children

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