Influence of arterial hypertension, smoking, and their combination on mortality (according to the results of a 27-year cohort prospective study of the unorganized population of Tomsk)

Долгалёв, И. В.; Бразовская, Н. Г.; Иванова, А. Ю.; Шипхинеева, А. Ю.; Богайчук, П. М.

doi:10.15829/1560-4071-2019-1-32-37

Cited by 10 publications

(13 citation statements)

References 11 publications

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“…Thus, in the Russian cohort study of residents of Tomsk I.V. Dolgalev et al showed that the risk of dying in persons with hypertension is 2.2 times higher than in persons without this disease [2]. It is known that the level of blood pressure (BP) per se plays an important prognostic role.…”

Section: Prevalence Of Hypertension In Russian Federation распространmentioning

confidence: 99%

“…Долгалев и соавт. показали, что риск умереть у лиц с АГ в 2,2 раза выше в сравнении с лицами, не имеющими этого заболевания [2]. Известно, что и уровень артериального давления (АД) per se играет важную прогностическую роль.…”

Section: Prevalence Of Hypertension In Russian Federation распространunclassified

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Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

Balanova

Шальнова

Imaeva

et al. 2019

Racionalʹnaâ farmakoterapiâ v kardiologii

116

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Participants of the study ESSE-RF-2 and co-authors: Moscow: Konstantinov V. V., Pokrovskaya M.S., Efimova I.A., Sivakova O.V.; Krasnodar: Alekseenko S.N., Gubarev S.V.; Оmsk: Livzan M.A., Grishechkina I.A., Rozhkova M.Yu.; Republic of Karelia: Vezikova N.N., Skopec I. S.; Ryazan: Filippov E.V., Dobrynina N.V., Nikulina N.N., Pereverzeva K.G., Moseychuk K.A.Aim. Evaluate the prevalence, awareness, treatment, and control of hypertension among people aged 25-64 examined in 4 regions of the Russian Federation. Material and methods. Study materials were the representative selections of non-organized male (n=3000) and female (n=3714) inhabitants of aged 25-64 from 4 regions of the Russian Federation (Krasnodar region, Omsk region, Ryazan region, the Republic of Karelia), response rate>80%. Systematic stratified multilevel random election was formed with locality criteria (Kisch method). All the participants were interviewed using the standard questionnaire. The universal epidemiological methods and evaluation criteria were used. The study was approved by the local ethics Committee of National research center for preventive medicine. Participants signed informed consent. Hypertension was defined as an average systolic blood pressure (SBP)≥140 mmHg and/or average diastolic blood pressure (DBP)≥90 mmHg and/or antihypertensive therapy (AHT). The efficacy of treatment was the achievement of the target BP. Control group – patients with BP<140/90 mmHg. Results. Mean SBP and DBP were 128.7±0,3 mmHg and 82.8±0.1 mmHg, respectively, higher BP was detected among male (p<0,001). The prevalence of hypertension was 44.2% that was higher among males than females (49.1% vs 39.9%, р˂0.0005), the highest hypertension frequency was in the Ryazan region. The awareness of hypertension was higher among females than in males 76.8% vs 69.4%. There were more persons with hypertension grade 1 among those, who were not aware of the hypertension. Medications were taken by 65.5% of females and 41.8% of males.Angiotensin-converting enzyme inhibitors were received by 49.9% of patients, angiotensin II receptor antagonists by 30.9%, beta blockers – 29.5%, diuretics – 22.7%, calcium antagonists – 15.7%, centrally acting drugs – 3.3%, others – 0.2%. The lack of AHT intake was negatively associated with age, ischemic heart disease, urban life and hypo-HDL especially among males. Heart rate >80 per min in females increased by 1.7 times the probability of absence of AHT. The prevalence of effectively treated was 49.7% of the participants with hypertension. The associations between ineffective treatment and abdominal obesity, ischemic heart disease (males), age, rural type of settlement, obesity (females) were found. Only 24.9% of patients had control of the hypertension.Conclusion. The prevalence of hypertension in Russian Federation remains high. An important task of the medical community is to identify the disease at an earlier stage of its development, before the appearance of complications. This approach can reduce the period from the onset of high blood pressure to a visit to the doctor.

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Section: Prevalence Of Hypertension In Russian Federation распространmentioning

confidence: 99%

Section: Prevalence Of Hypertension In Russian Federation распространunclassified

Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

Balanova

Шальнова

Imaeva

et al. 2019

Racionalʹnaâ farmakoterapiâ v kardiologii

116

View full text Add to dashboard Cite

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“…A negative relationship between BMI and smoking has been confirmed in many studies; (15,16) nevertheless, it has been shown that smoking is an independent risk factor for the development of cardiovascular diseases, including stroke and coronary heart disease. (12,(24)(25)(26) Table 1 presents a comparative analysis of overweight and obesity in the general population, depending on gender and on the status of smoking. The frequency of overweight in the general population of smokers was higher than in nonsmokers due to the higher rate of obesity among female smokers; however, the differences are statistically insignificant.…”

Section: Resultsmentioning

confidence: 99%

Cigarette Smoking and Components of the Metabolic Syndrome in the Indigenous Population of the Arctic Territory of Yakutia

Sofronova¹,

Kirillina²,

Николаев³

et al. 2020

IJBM

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The aim of this research was to study the influence of smoking on components of the metabolic syndrome and their relationship in the indigenous population of the Arctic territory of Yakutia. Methods and Results: The material for the study was collected under expeditionary conditions in the Arctic territory of Yakutia in places of compact residence of indigenous peoples. Using the continuous method, we examined 348 subjects (225 women and 123 men). The average age of the respondents was 48.16±0.52 years (49.71±0.63 years for women and 44.98±0.91 years for men). The research program included the following sections: a questionnaire for objective assessment of state; anthropometric examination; assessment of blood pressure (BP); determination of insulin and fasting glucose. In the survey, only those who smoked at least 1 cigarette per day during the last 12 months were considered smokers. The obtained results indicate that the indigenous population of the northern territory of Yakutia has a high frequency of risk factors for the development of cardiovascular pathology, such as overweight, obesity, and smoking. Overweight is equally common in both men and women; obesity is almost 2.5 times more common in women. An increase in body weight and systolic BP is not associated with smoking; however, the simultaneous combination of all these factors can affect the risk of cardiovascular incidents. A negative relationship between BMI and smoking was found. An increased index of insulin resistance is associated with the simultaneous spread of obesity among nonsmokers. The same association of glucose level with BP was obtained in both smokers and nonsmokers. Conclusion: Metabolic disorders in the indigenous population of the northern territory of Yakutia are caused by a change in the traditional way of life and nutrition, with a decrease in physical activity and a lack of adherence to a healthy lifestyle.

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“…При этом, если у мужчин чаще наблюдалось курение, то у женщин чаще регистрировался высокий уровень холестерина и ожирение [14]. Согласно данным 27-летнего исследования, проведенного в Томске, сочетание курения и повышенного АД приво-Primary Prevention of CVD Первичная профилактика ССЗ дит к увеличению относительного риска общей и сердечно-сосудистой смертности в 5 раз [15]. В 2019 г. эксперты American College of Cardiology (ACC) представили упрощенную версию рекомендаций AHA, названных в виде аббревиатуры "ABCDE", отражающих первые буквы ведущих факторов риска ССЗ [16].…”

Section: шкалы для стратификации риска ссзunclassified

“…Кроме того, результаты 27-летнего исследования, проведенного в Томске с участием 1546 человек, показали, что ОР общей смертности у обследуемых лиц с АГ увеличивается в 2,2 раза, в то время как при сочетании с курением -в 5,2 раза. При этом у пациентов, бросивших курить, отмечался риск смерти от ССЗ в 1,8 раз выше по сравнению с некурящими [28].…”

Section: курениеunclassified

Possible Approaches to Primary Prevention of Cardiovascular Diseases

Ларина

Мкртычев

Кузнецова

et al. 2020

Racionalʹnaâ farmakoterapiâ v kardiologii

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In recent years there is a positive trend in the development of preventive medicine, in particular, primary prevention of diseases. However, in most cases, patients seek help from a doctor after the manifestation of the disease, and therefore, early identification of risk factors (RF) remains relevant. Conduction of a large number of studies that are aimed at studying modifiable RF associated with the development of cardiovascular diseases (CVD), allowed the experts of the American Heart Association to develop recommendations “Life's Simple 7”, which makes it possible to structure methods of primary prevention of CVD and minimize the risk of their development. In 2019, experts from the American College of Cardiology presented a simplified version of these recommendations, to improve approaches to primary prevention and their effectiveness not only for doctors but also for patients. Thus, by involving the patient in the decision-making process about follow-up treatment, doctors can achieve a high level of compliance, which is essential for improving the prognosis. The “ABCDE” recommendations, in name of which are reflected the first letters of the leading CVD RF, include such paragraphs as RF assessment, the use of antiaggregating therapy, correction of blood pressure, cholesterol levels, smoking elimination, correction of high glucose levels and diabetes treatment, weight loss, assessment of social and economic factors affecting the morbidity in a particular patient. Despite the undoubted benefit of the “ABCDE” recommendations, some problems of primary prevention currently cannot be solved: the inability to accurately assess social and economic RF; the imperfection of the used CVD risk scales. The updated version of the recommendations allows not only to assess the existing RF of the patient, but also to effectively correct them. In addition, the patient himself can read the recommendations, which improves understanding of the primary prevention importance.

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Influence of arterial hypertension, smoking, and their combination on mortality (according to the results of a 27-year cohort prospective study of the unorganized population of Tomsk)

Cited by 10 publications

References 11 publications

Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

Cigarette Smoking and Components of the Metabolic Syndrome in the Indigenous Population of the Arctic Territory of Yakutia

Possible Approaches to Primary Prevention of Cardiovascular Diseases

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