Influence of Bariatric Surgery on Erectile Dysfunction—a Systematic Review and Meta-Analysis

Małczak, Piotr; Wysocki, Michał; Pisarska-Adamczyk, Magdalena; Strojek, Jakub; Rodak, Hanna; Lastovetskyi, Ilie; Pędziwiatr, Michał; Major, Piotr

doi:10.1007/s11695-023-06572-9

Cited by 6 publications

(1 citation statement)

References 34 publications

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“…A recent systematic review involving 14 studies and 508 patients clearly showed remarkable benefits of improvement of T levels and erectile function in patients following weight loss after bariatric surgery[ 40 ]. Trials evaluating the effect of MBS on semen morphology are highly variable and inconsistent, with small prospective studies reporting a decrease in the percentage of sperm with normal morphology.…”

Section: Bariatric Surgerymentioning

confidence: 99%

Management of male obesity-related secondary hypogonadism: A clinical update

Shenoy,

Mondal,

Fernandez

et al. 2024

World J Exp Med

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The global obesity pandemic has resulted in a rise in the prevalence of male obesity-related secondary hypogonadism (MOSH) with emerging evidence on the role of testosterone therapy. We aim to provide an updated and practical approach towards its management. We did a comprehensive literature search across MEDLINE (via PubMed), Scopus, and Google Scholar databases using the keywords “MOSH” OR “Obesity-related hypogonadism” OR “Testosterone replacement therapy” OR “Selective estrogen receptor modulator” OR “SERM” OR “Guidelines on male hypogonadism” as well as a manual search of references within the articles. A narrative review based on available evidence, recommendations and their practical implications was done. Although weight loss is the ideal therapeutic strategy for patients with MOSH, achievement of significant weight reduction is usually difficult with lifestyle changes alone in real-world practice. Therefore, androgen administration is often necessary in the management of hypogonadism in patients with MOSH which also improves many other comorbidities related to obesity. However, there is conflicting evidence for the appropriate use of testosterone replacement therapy (TRT), and it can also be associated with complications. This evidence-based review updates the available evidence including the very recently published results of the TRAVERSE trial and provides comprehensive clinical practice pearls for the management of patients with MOSH. Before starting testosterone replacement in functional hypogonadism of obesity, it would be desirable to initiate lifestyle modification to ensure weight reduction. TRT should be coupled with the management of other comorbidities related to obesity in MOSH patients. Balancing the risks and benefits of TRT should be considered in every patient before and during long-term management.

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Section: Bariatric Surgerymentioning

confidence: 99%