Influence of beta-blocker use on percentage of target heart rate exercise prescription

Wonisch, Manfred; Hofmann, Peter; Fruhwald, Friedrich; Kraxner, Wilfried; H??dl, Ronald; Pokan, Rochus; Klein, W.

doi:10.1097/00149831-200308000-00013

Cited by 92 publications

(61 citation statements)

References 22 publications

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“…6). Verschiedene Methoden zur Ermittlung der aeroben und anaeroben Schwelle unter Verwendung der Atemgasanalyse, der Blutlaktatkonzentration oder der Herzfrequenz sind in der Literatur beschrieben [11,12,[45][46][47][48].…”

Section: Ekgunclassified

Praxisleitlinien Ergometrie

Wonisch¹,

Berent²,

Klicpera³

et al. 2014

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Section: Ekgunclassified

Praxisleitlinien Ergometrie

Wonisch¹,

Berent²,

Klicpera³

et al. 2014

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“…It is well known that $-blockers blunt HR responses and blood pressures to exercise, but not oxygen consumption. 45,46 Although 6 participants were using $-blockers, they were evenly distributed to the intervention and control groups, and the overall number was limited. Thus, this would not have affected the group differences and any significant differences in the findings of this study.…”

Section: N Limitations and Strengthsmentioning

confidence: 99%

Cardiopulmonary Responses and Adherence to Exercise in Women Newly Diagnosed With Breast Cancer Undergoing Adjuvant Therapy

et al. 2006

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Adherence to exercise Adjuvant therapy Breast cancer Cardiopulmonary responsesCardiopulmonary responses to an 8-week moderate-intensity aerobic exercise intervention and adherence to exercise during and after intervention were assessed in 41 women newly diagnosed with breast cancer undergoing adjuvant therapy. The intervention was primarily aimed at minimizing deconditioning. Women were randomly assigned to the intervention or control group, completed graded exercise tests before and after intervention, and encouraged to continue their exercise postintervention. Over time, only the intervention group showed significant decreases in resting heart rate, resting systolic blood pressure (SBP), P G .05 each, and maximum SBP, P G .02, and an increase in VO 2 peak, P G .001, although resting SBP was higher in the intervention group at both timepoints, P G .05. The adherence rate to 8-week exercise intervention was 78.3% with average weekly attendance of 2.4 sessions and 42.7 minutes (27.8 minutes within target heart rate) exercise per session. Overall physical activity levels over 16 weeks postintervention did not differ between 2 groups. However, the within-group analysis indicated that only the intervention group showed a significant increase in voluntary activity, P G .02, and energy expenditure, P G .02, and a decrease in sedentary activity, P G .02. These findings indicate that moderate-intensity aerobic exercise is beneficial in reducing deconditioning of cardiopulmonary responses in newly diagnosed breast cancer women undergoing adjuvant therapy.156 n Cancer Nursing TM

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“…17 In a small study of 10 young healthy men, a small dose of bisoprolol given for 2 weeks reduced the percentage of maximal heart rate at the aerobic and anaerobic threshold. 18 Thus, it may be speculated that cardiovascular benefits of exercise at a defined heart rate differ in the absence and presence of beta-blockade. The aim of the present study is to determine the differential effects of lactate-based exercise prescription on hypertensives with or without chronic betablockade.…”

Section: Introductionmentioning

confidence: 99%

Beta-blockers do not impair the cardiovascular benefits of endurance training in hypertensives

et al. 2007

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Aerobic physical exercise is broadly recommended as a helpful adjunct to obtain blood pressure control in hypertension. Beta-blockade interacts with heart rate, sympathetic tone, maximal workload and local lactate production. In the present randomized-controlled study, we compared the cardiovascular effects of an endurance training programme in elderly hypertensives with or without beta-blockers and developed a first approach to determine a lactate-based training heart rate in presence of beta-blockade. Fifty-two patients (23 with beta-blocker, 29 without beta-blocker) X60 years with systolic 24-h ambulatory blood pressure (ABP) X140 mm Hg and/or antihypertensive treatment were randomly assigned to sedentary activity or a heart-rate controlled 12-week treadmill exercise programme (lactate 2.0 mmol/l). In the exercise group, the training significantly decreased systolic and diastolic 24-h ABP, blood pressure on exertion (100 W) and increased endothelium-dependent vasodilation (flow-mediated vasodilation, FMD) and physical performance both in the presence and absence of beta-blockade (Po0.05 each). The extent of ABP reduction did not significantly differ in the presence or absence of beta-blockade (D systolic ABP 10.6710.5 vs 10.678.8 mm Hg, D diastolic ABP 5.778.6 vs 5.874.0 mm Hg). Mean training heart rate was significantly lower in the patients on beta-blockers (97.277.7 vs 118.377.5/min, Po0.001). Lactate-based aerobic endurance training evokes comparable cardiovascular benefits in the presence and absence of beta-blockade including a marked improvement of endothelial function. In the present study, target training heart rate with beta-blockers is about 18% lower than without.

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Influence of beta-blocker use on percentage of target heart rate exercise prescription

Cited by 92 publications

References 22 publications

Praxisleitlinien Ergometrie

Praxisleitlinien Ergometrie

Cardiopulmonary Responses and Adherence to Exercise in Women Newly Diagnosed With Breast Cancer Undergoing Adjuvant Therapy

Beta-blockers do not impair the cardiovascular benefits of endurance training in hypertensives

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