Influence of beta cyclodextrin on amlodipine-BSA interaction: A spectroscopic and molecular docking study

Shinde, Mandakini; Kale, Kishor B.; Yadav, Pooja; Suryawanshi, Manjoosha; Ottoor, Divya

doi:10.1016/j.cdc.2022.100945

Cited by 5 publications

(1 citation statement)

References 32 publications

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“…Thermodynamic parameters such as enthalpy change (∆H), entropy change (∆S), and Gibbs free energy (∆G) can determine the characteristics of the interaction. These parameters can be calculated by the Van't Hoff equation and the thermodynamic equation as follows [26]:…”

Section: Thermodynamic Parameters and Force Types Of Interaction Betw...mentioning

confidence: 99%

Studies of Interactions between Beta-Cyfluthrin and BSA Based on Fluorescence Spectrometry and Ultraviolet Degradation

Wang,

et al. 2023

Photonics

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Pesticides play a pivotal role in modern agriculture, but their potential environmental and health impacts necessitate a comprehensive understanding of their interactions with biological molecules. Beta-cyfluthrin, a widely used synthetic pyrethroid insecticide, is known for its efficiency in pest control. However, its interaction with bovine serum albumin (BSA), a crucial transport protein in living organisms, has not been extensively studied. The interaction between beta-cyfluthrin, a prominent synthetic pyrethroid insecticide, and bovine serum albumin (BSA) was comprehensively investigated using fluorescence spectrometry. Furthermore, the influence of ultraviolet (UV) degradation on the interaction parameters was explored, enhancing our understanding of the impact of environmental conditions on this interaction. The Stern–Volmer equation was employed to determine quenching constants, revealing that the fluorescence quenching mechanism primarily involved static quenching. The temperature variations were studied, showing an increase in the binding constant with rising temperature prior to degradation, while post-UV degradation, an inverse correlation between the binding constant and temperature was observed. The thermodynamic parameters were derived through appropriate equations, unveiling the underlying reaction forces. In the absence of degradation, hydrophobic interactions dominated, whereas after UV degradation, interactions shifted to hydrogen bonding and van der Waals forces. The findings elucidate the nuanced effects of UV degradation on the interaction between beta-cyfluthrin and BSA. This study furnishes critical insights that serve as a scientific foundation for pesticide production and application strategies, accounting for the influence of UV degradation on the intricate interplay between pesticides and BSA.

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Section: Thermodynamic Parameters and Force Types Of Interaction Betw...mentioning

confidence: 99%

Studies of Interactions between Beta-Cyfluthrin and BSA Based on Fluorescence Spectrometry and Ultraviolet Degradation

Wang,

et al. 2023

Photonics

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Synthesis of water-soluble novel bioactive pyridine-based azo coumarin derivative and competitive cytotoxicity, DNA binding, BSA binding study, and in silico analysis with coumarin

Karan

Shit

Panja

et al. 2023

Bioorganic Chemistry

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Probing berberine syringate-bovine serum albumin interactions by multi-spectroscopic, conductimetric, volumetric and molecular docking methods

Hu,

Yan,

2024

Journal of Molecular Liquids

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Influence of beta cyclodextrin on amlodipine-BSA interaction: A spectroscopic and molecular docking study

Cited by 5 publications

References 32 publications

Studies of Interactions between Beta-Cyfluthrin and BSA Based on Fluorescence Spectrometry and Ultraviolet Degradation

Studies of Interactions between Beta-Cyfluthrin and BSA Based on Fluorescence Spectrometry and Ultraviolet Degradation

Synthesis of water-soluble novel bioactive pyridine-based azo coumarin derivative and competitive cytotoxicity, DNA binding, BSA binding study, and in silico analysis with coumarin

Probing berberine syringate-bovine serum albumin interactions by multi-spectroscopic, conductimetric, volumetric and molecular docking methods

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