Non-synchronous blade vibration (NSV) has received enormous attention in turbomachinery research, since it can be safety critical and its occurrence is less predictable than typical aeroelastic instabilities such as flutter. Typical for front stages of core compressors, NSV arises due to the propagation of one or multiple aerodynamic disturbances, traveling around the circumference and locking-in with structural blade vibration modes. Recent studies have shown, that modern low-speed fan architectures are also susceptible for this type of instability. With a specific focus on such aeroelastic instabilities, the open-test-case fan stage ECL5 has been designed by Ecole Centrale de Lyon. It is representative of near-future UHBR fan concepts with carbon-fibre composite blades. To prepare the experiments planned for 2022, unsteady full-annulus simulations have been carried out. Depending on rotation speed, the emergence of aerodynamic disturbances traveling around the circumference at a typical convective speed is observed, such as reported in studies on NSV on different configurations. These aerodynamic disturbances are identified as a possible source for non-synchronous vibration. At design conditions, an unstable aerodynamic behavior is observed, with part-span stall cells developing within the operating range predicted by RANS simulations. A study of intentional aerodynamic mistuning, in form of an alternating leading edge pattern is presented. At design speed, influence on steady performance and the onset of part-span stall is observed. At part-speed, the evolution of small-scale vortical disturbances, which can be responsible for the onset of NSV is affected significantly, providing a possible method to suppress NSV.