Influence of catheter design on lumen wall temperature distribution in intracoronary thermography

Have, Antoinette G. ten; Draaijers, Erasmus B.G.T.; Gijsen, Frank; Wentzel, Jolanda J.; Slager, Cornelis J.; Serruys, Patrick W.; Steen, Antonius F.W. van der

doi:10.1016/j.jbiomech.2006.01.016

Cited by 8 publications

(2 citation statements)

References 20 publications

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“…181,182 It has been learned that coronary blood flow and catheter design features complicate measurement of plaque temperature in vivo. 183 Blood flow is a coolant for the heart, which generates heat as a result of its contraction. 184 This cooling effect makes it difficult to measure relatively small increases in plaque temperature without interrupting blood flow.…”

Section: Thermographymentioning

confidence: 99%

Detection and Treatment of Vulnerable Plaques and Vulnerable Patients

2006

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Section: Thermographymentioning

confidence: 99%

Detection and Treatment of Vulnerable Plaques and Vulnerable Patients

2006

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“…Accordingly, another mathematical simulation of a model of a coronary artery segment also containing a heat source predicted that measured temperature is strongly affected by blood flow, cap thickness, source geometry, and maximal flow velocity. In specific, maximal temperature differences at the lumen wall decreased when the source volume increased and blood flow was acting as a coolant to the lumen wall [47]. Additionally, when cap thickness increased, maximal temperatures decreased and the influence of flow increased.…”

Section: Effect Of Blood Flow On Coronary Temperature Measurementmentioning

confidence: 95%

Intravascular Thermography for Assessing Vulnerable Plaques

Toutouzas

Drakopoulou

Synetos

et al. 2010

curr cardiovasc imaging rep

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Atherosclerosis and its cardiovascular complications remain the leading cause of death in developed countries. Current knowledge of coronary artery disease progression has significantly evolved and the interest has been focused on the development of new imaging techniques for the early detection of vulnerable lesions. Intracoronary thermography is a method that detects local plaque inflammation. Clinical studies with intracoronary thermography have enlightened the diagnostic algorithm of high-risk or "vulnerable" plaque. The current shortcomings, however, of intracoronary thermography limit the clinical application of the method. Future technological achievements will hopefully lead to the detection of inflamed plaques, thus determining the role of inflammation in plaque destabilization and directing local and/or systemic therapy in patients with coronary artery disease.

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