Influence of Combined Effect of Constant Illumination and Chronic Alcohol Intoxication on Hepatocyte Ultrastructure in Male and Female Wistar Rats
David Aleksandrovich Areshidze,
Lyudmila Mikhaylovna Mikhaleva,
Lev Vladimirovich Kakturskiy
et al.
Abstract:Light pollution causes melatonin deficiency and circadian rhythm disruption. Thus, it is associated with hepatopathy. Circadian rhythm disruption increases liver damage from alcohol and the severity of alcoholism.
The aim of the study was to examine the combined effect of constant illumination and chronic alcohol intoxication (CAI) on hepatocyte ultrastructure in male and female rats.
Materials and Methods. The study was carried out on 120 male and 80 female Wistar outbred rats aged 6 months. The e… Show more
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