Influence of composition and powder/water ratio on adhesion strength and initial viscosity of powder-type denture adhesives based on CMC-Na and PVM-MA

Okazaki, Hitomi; Yoshida, Kazuhiro; Egoshi, Takafumi; Takase, Kazuma; Murata, Hiroshi

doi:10.4012/dmj.2018-307

Cited by 10 publications

(8 citation statements)

References 30 publications

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“…Bioadhesive polymers are often used for controlling release of medical and dental therapeutic agents. PVM/MA copolymer has been widely used in dentistry [ 17 , 21 – 23 ], and its bioadhesive properties are related to the formation of carboxylic groups from the polyanhydride residues of the copolymer [ 24 ]. It has been shown that dentifrice containing PVM/MA copolymers could improve the retention of fluoride after a single brushing application compared to those without bioadhesive copolymers[ 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Polyvinyl methyl ether / maleic acid (PVM/MA) copolymer is a widely used bioadhesive molecule. Its tissue adhesion characters have been utilized in denture adhesives [ 17 ], anti-gingivitis or desensitizing mouthwashes [ 10 , 18 ]. When combined with inorganic fillers, PVM/MA performed better in dentine tubule occlusion than products that contained either the fillers or the copolymers alone [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

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Effects of desensitizing dentifrices on dentin tubule occlusion and resistance to erosive challenges

et al. 2021

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Background Many studies have demonstrated efficacy of casein phosphopeptide (CPP) containing products for dentin tubule occlusion for treatment of dentin sensitivity, but their effectiveness under dynamic erosive challenges remains to be elucidated. The purpose of the present study was to investigate the effectiveness of a desensitizing dentifrice containing CPP in occluding dentin tubules and resisting erosive challenges in comparison to that containing polyvinyl methyl ether/maleic acid (PVM/MA) copolymers. Methods A total of 33 dentin discs were prepared from coronal sections of human third molars and divided into 3 groups: a toothpaste containing CPP; a toothpaste containing PVM/MA and submicron silica; and a regular toothpaste (Controls). A soft-bristle toothbrush was used to brush the dentin discs with the dentifrices for 45 strokes in 30 s at a force of approximately 200 g. The brushing cycle was repeated after immersion of the dentin discs in artificial saliva overnight. The dentin discs were then challenged in orange juice for 10 min in an incubator rocking at 120 rpm. Three fields were randomly selected on each dentin disk surface to assess dentin tubule occlusions after each brushing cycle and after orange juice challenge with a 3D laser scanning microscope. Specimen cross sections were examined with a scanning electron microscope equipped with energy dispersive spectroscopy (SEM/EDS). Results After the first and second cycles of brushing, dentin tubules were occluded on average by 56.3% and 85.7% in CPP group, 66.2% and 88.1% in PVM/MA group, and 0.0 and 13.0% in the controls, respectively. There were no statistically significant differences in dentin tubule occlusions between the CPP and PVM/MA groups after two cycles of brushing (p>0.05). After dynamic erosive challenges with orange juice, 20.3% of the dentin tubules in the CPP group, 79.1% in the PVM/MA group and none in the control remained occluded (P<0.05). SEM/EDS imaging showed that dentin tubules were blocked with plugs containing dentifrice substances in CPP and PVM/MA groups after treatments, but none in the controls. Conclusions Desensitizing dentifrices containing CPP or PVM/MA could effectively occlude dentin tubules after two cycles of brushing. PVM/MA in combination with submicron silicon dioxide exhibited stronger resistance to dynamic erosive challenges by acidic beverages. Inorganic fillers that can enter dentin tubules and resist erosive challenges may be key for desensitizing dentifrices.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of desensitizing dentifrices on dentin tubule occlusion and resistance to erosive challenges

et al. 2021

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“…A liner type (cushion form) denture adhesive consists of a non-aqueous paste of polyvinyl acetate and ethyl alcohol, and it improves the retention and stability by filling the gap between the denture intaglio surface of ill-fitting dentures and the basal seat mucosa [7]. Generally, the use of both powder-and cream-type denture adhesives, rather than the liner type, is recommended for clinical cases, because both powder-and cream-type denture adhesives produce a thin layer of denture adhesive while minimally changing the occlusal relationship after application [8].…”

Section: Introductionmentioning

confidence: 99%

Effects of denture adhesives on denture retention and occlusal forces in complete denture wearers: A multicenter, randomized controlled trial

et al. 2023

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This study aimed to determine the effects of denture adhesives on denture retention and occlusal force in complete denture wearers in a multicenter, randomized, parallel-group controlled trial. Methods: Two hundred edentulous patients wearing complete dentures were allocated to three groups: powder-type denture adhesive, cream-type denture adhesive, and control (saline solution). Denture adhesives and saline solution were applied to the dentures for 4 days. The retentive force of the dentures and occlusal force were measured using a force transducer occlusal force meter at baseline and after 4 days of intervention. In addition to between-group comparisons, subgroup analyses of denture retention and occlusal force were performed based on the level of difficulty of the edentulism treatment. The levels were ranked as I (easy), II, III, and IV (difficult). Results: Cream-type denture adhesives significantly improved the retentive force of the dentures (P<0.01) and occlusal force (P<0.05), with no significant differences between baseline and post-intervention forces in the powder-type denture adhesive and control groups. In within-group comparisons, cream-type denture adhesives improved both the retentive and occlusal forces at Level II (P<0.05), and powder-type denture adhesives improved the occlusal force at Level II (P<0.01). Conclusions: Application of cream-type denture adhesives effectively improves the denture retention and occlusal force in complete denture wearers with a moderate degree of difficulty during edentulism treatment.

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“…The main purpose of the antimicrobials, such as sodium borate, sodium tetraborate, hexachlorophene or propyl hydroxybenzoate, is to prevent the appearance of Candida Albicans fungal infections because some studies have shown that the use of denture adhesives increased its growth 3,7 . Finally, the additives that serve as fillers, such as magnesium oxide, in addition to moistening, are intended to impart a pleasant taste for the user (e.g., mint or gaultheria oil) 8,9 …”

mentioning

confidence: 99%

“…3,7 Finally, the additives that serve as fillers, such as magnesium oxide, in addition to moistening, are intended to impart a pleasant taste for the user (e.g., mint or gaultheria oil). 8,9 Denture adhesives are sold both as creams and powders. 10 This study was focused on the use of cream format adhesives because they have more bond strength and the time in contact with the oral mucosa is longer than in the case of a powder.…”

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confidence: 99%

Are Denture Adhesives Safe for Oral Cells?

López‐García

Pecci-Lloret

García‐Bernal

et al. 2020

Journal of Prosthodontics

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Purpose To compare the cytotoxicity of six commercially available denture adhesives on human gingival cells: Poligrip Flavour Free Fixative Cream, Fixodent Pro Duo Protection, Novafix cream, FittyDent, Polident Total Action, and Fixodent Pro Plus Duo Protection. Material and Methods Eluates of denture adhesives were brought into contact with human gingival cells and compared to untreated cells (w/o any dental adhesive elute). Cell toxicity was assessed by measuring cell viability (3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide) (MTT) assays), cell morphology (immunofluorescence assays), induction of apoptosis/necrosis and production of reactive oxygen species (ROS) (flow cytometry assays). In addition, the pH of each sample was determined. Data were analyzed using one‐way analysis of variance (ANOVA) followed by Dunnett's multiple comparisons test. Results All denture adhesives tested led to a reduction in pH, especially Fixodent Pro Duo Protection and Fixodent Pro Plus Duo Protection. The cell viability assays showed that Fixodent Pro Duo Protection (1:1 72 hours, p = 3.04 × 10−6; 1:2 72 hours, p = 2.07 × 10−6; 1:4 72 hours, p = 2.04 × 10−6) and Fixodent Pro Plus Duo Protection (1:1 72 hours, p = 2.01 × 10−6; 1:2 72 hours, p = 3.03 × 10−6; 1:4 72 hours, p = 2.02 × 10−6) significantly decreased cell viability at all dilutions. Compared to the control group and the rest of the adhesives, Poligrip Flavour Free Fixative Cream (PFF 1:1 72 hours, p = 2.24 × 10−6; 1:2 72 hours, p = 2.44 × 10−6; 1:4 72 hours, p = 2.04 × 10−6) showed a significantly higher cell viability score at all dilutions. Fixodent Pro Duo Protection and Fixodent Pro Plus Duo Protection, both adhesives containing zinc salts in their composition, were responsible for necrosis, and the number of cells was much reduced, with aberrant morphology and pyknotic nucleus. Finally, Fixodent (1:2, p = 2.04 × 10−6, 1:4, p = 0.00036; 1:2, p = 8.82 × 10−6, 1:4, p = 2.30 × 10−6) products significantly promoted ROS production in gingival cells. Conclusions The results suggest that denture adhesives containing zinc in their composition could be responsible of the decrease of cell viability, ROS production, aberrant cell morphology, and induction of apoptosis and cell death. However, other possible additional cytotoxic factors must be considered. Thus, more studies are necessary to confirm this hypothesis.

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Influence of composition and powder/water ratio on adhesion strength and initial viscosity of powder-type denture adhesives based on CMC-Na and PVM-MA

Cited by 10 publications

References 30 publications

Effects of desensitizing dentifrices on dentin tubule occlusion and resistance to erosive challenges

Effects of desensitizing dentifrices on dentin tubule occlusion and resistance to erosive challenges

Effects of denture adhesives on denture retention and occlusal forces in complete denture wearers: A multicenter, randomized controlled trial

Are Denture Adhesives Safe for Oral Cells?

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