Influence of contact lens material surface characteristics on replacement frequency

Bleshoy, Hans; Guillon, Michel; Shah, Dipti

doi:10.1016/0892-8967(94)90004-3

Cited by 16 publications

(5 citation statements)

References 8 publications

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“…1,2 The deposited material includes a wide variety of proteins, lipids and mucins, [3][4][5][6][7][8][9][10][11][12] and considerable evidence exists to indicate that contact lens deposits reduce visual performance, 13 comfort [14][15][16] and in-eye wettability 17 and produce increased inflammatory complications. [18][19][20] The deposition of proteins and lipids onto contact lenses occurs rapidly [21][22][23] and the underlying principles governing this deposition are highly complex and dependent upon a number of factors.…”

Section: Introductionmentioning

confidence: 99%

Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials

Senchyna

Jones

Louie

et al. 2004

Current Eye Research

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Section: Introductionmentioning

confidence: 99%

Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials

Senchyna

Jones

Louie

et al. 2004

Current Eye Research

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“…[25][26][27] Use of the Tearscope and video topography can determine the PL NIBUT non-invasive surface dry-up time. [28][29][30][31][32][33][34] Pre-lens tear film can be analyzed by interferometry, including thin film, Twyman-Green interferometry and lateral sharing interferometry. 35,36 Furthermore, changes and irregularities in tear film thickness can be evaluated by aberrometry.…”

Section: Introductionmentioning

confidence: 99%

<p>Objective Analysis of Pre-Lens Tear Film Stability of Daily Disposable Contact Lenses Using Ring Mire Projection</p>

Marx¹,

Wittekind²,

Sickenberger³

2020

OPTO

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Purpose: The primary objective of this study was to evaluate the in vivo pre-lens noninvasive drying-up time of two types of daily disposable contact lenses (DDCLs) after 12 hours of wear. Methods: This prospective, randomized, single-center, cross-over pilot study evaluated 31 subjects aged 18-44 years with normal eyes and good tear film stability who were adapted current soft contact lens wearers. Subjects wore nelfilcon A and stenfilcon A DDCLs for 12 hours each on two different days. Non-invasive video keratography drying-up time (NIK-DUT) videos of each eye were recorded 12 hours after lens insertion for about 25 seconds, with a 5-minute tear film recovery time allowed between video recordings of the right and left eyes to avoid bias. Post-blink time required to reach 15% distortion of the projected rings and the speed of break-up at 15 seconds post-blink were measured at each time point and oneye wettability was determined by ring mire projection under white light illumination. Results: Mean time to reach 15% ring distortion was similar for nelfilcon A (19.25±3.20 sec) and stenfilcon A (20.24±3.02 sec) DDCLs but varied highly among subjects. The mean speed of break-up at 15 sec post-blink was 0.3±0.38% distortion/sec (95% confidence interval [CI] 0.138-0.365% distortion/sec) for nelfilcon A and 0.2±0.23% distortion/sec (95% CI 0.048-0.279% distortion/sec) for stenfilcon A DDCLs. Conclusion: Multifunctional topography allowed the objective evaluation of in vivo prelens tear film stability using ring mire projection. This dynamic method was simple, fast and non-invasive, enabling measurements of NIK-DUT and evaluating wettability over a large area, greater than the optical zone of the contact lens surface, for the entire inter-blink interval.

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“…The adsorption of proteins at the surface of the lens sitting in the tear fluid on the cornea is a well‐known problem resulting in a wearing comfort reduction, increased inflammatory responses, microbial keratitis, and the development of papillary conjunctivitis . Last but not least, the protein deposition can disturb the optical clarity of the lens .…”

Section: Introductionmentioning

confidence: 99%

“…A decreasing wettability and a high protein adsorption are the two major factors limiting the long term wearing comfort of CLs. [1] A high wettability of the lens is essential and is immediately positively perceived by the contact lens wearer when placing a CL on the cornea in terms of the initial [2] as well as the long-term wearing comfort. The in vitro wettability is often used to predict the in vivo behavior of the CL and gives a first insight on how the tear film covers the lens surface.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Nanofilms Produced by Magnetron Enhanced Plasma Polymerization from Methane and Oxygen for Coating of Rigid Contact Lenses

Bergmann

Ledernez

Dame

et al. 2013

Plasma Processes & Polymers

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Although soft contact lenses are more widespread, rigid contact lenses have been around for decades and their materials have been greatly improved, especially in terms of oxygen permeability. Protein adsorption and wettability are, however, complex challenges still faced by both soft and rigid contact lenses (CLs). This study aims at improving these two major attributes by means of a low‐pressure magnetron enhanced 15 kHz plasma polymerization process. The wide parameter range of the process allowed the tailoring of the surface properties and delivered stable, reproducible plasma coatings. The XPS, FT‐IR, WCA, and QCM surface analysis methods were used to study the nanofilms. A contact angle of down to 18° and a protein (lysozyme) adsorption of only 0.2 µg cm−2 were achieved. Some correlations with the more commonly used “PEO‐like” coatings helped to explain the measurement results.

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Influence of contact lens material surface characteristics on replacement frequency

Cited by 16 publications

References 8 publications

Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials

Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials

<p>Objective Analysis of Pre-Lens Tear Film Stability of Daily Disposable Contact Lenses Using Ring Mire Projection</p>

Nanofilms Produced by Magnetron Enhanced Plasma Polymerization from Methane and Oxygen for Coating of Rigid Contact Lenses

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