Influence of controlled immediate loading and implant design on peri‐implant bone formation

Abstract

Well-controlled immediate implant loading accelerates tissue mineralization at the interface. Adequate bone stimulation via mechanical coupling may account for the larger bone response around the screw-type implant compared with the cylindrical implant.

Bone ingrowth on the surface of endosseous implants. Part 2: Theoretical and numerical analysis

“…Secondly, we evaluate how the implant geometry can affect the formation of bone, not only by changing the stresses and strains of the surrounding tissue, what has been experimentally verified (Vandamme et al, 2007), but also by altering certain biological phenomena, such as growth factor diffusion or the direction of cell migration.…”

Clinical and radiographic evaluation of NobelActiveTM dental implants

“…Implant design features such as thread pitch, thread geometry, helix angle, thread depth and width may also affect implant stability (Abuhussein et al 2010). The screw or "threaded" design minimises implant micromotion during function ) and also increases the surface area of the implant for bone-to-implant contact, compared to cylindrical implants (Vandamme et al 2007). Additionally, tapered implant designs bring higher primary stability than straight cylindrical implant geometry as they may provide a degree of compression of the cortical bone in a poor bone implant site (O 'Sullivan et al 2004b).…”

Peri-implant bone mechanobiology. Review of the literature

“…Vandamme et al found that the BFA was larger in loaded versus unloaded implants and found a higher value in those subjected to an a�ial displacement of 90 µm (9,12). A significant difference in application time between loaded and non-loaded implants was reported by these authors but was not observed by Duyck et al (13).…”

“…Vandamme et al (9,10,12) found a higher B�C value in loaded versus non-loaded implants. �n contrast, Duyck et al reported a lower B�C value in loaded implants, using a similar study design and duplicating the load cycles, suggesting that a loading of less than 800 cycles produces an increase in the B�C, although the e�act limit was not defined (15).…”

“…�owever, it is now known that mechanical stimuli have a marked influence on cells involved in osteogenesis, such as osteocytes (1,2), osteoblasts (3)(4)(5), and undifferentiated mesenchymal cells (6,7). �n vivo studies have shown that the immediate application of a mechanical load during the bone regeneration phase has a beneficial effect on osseointegration (8)(9)(10)(11)(12)(13)(14)(15). Nevertheless, there are few data on devices that take advantage of this osteogenic capacity of mechanical e678 stimuli in implant treatments or on the most effective application mode.…”