a b s t r a c tIn this paper, laminar forced convection flow of Al 2 O 3 -water nanofluid in sinusoidal-wavy channel is numerically studied. The two-dimensional governing equations of continuity, momentum and energy equations in body-fitted coordinates are solved using finite volume method. The sinusoidal-wavy channel with four different phase shifts of 01, 451, 901 and 1801 are considered in this study. The results of numerical solution are obtained for Reynolds number and nanoparticle volume fractions ranges of 100-800 and 0-5%, respectively. The effect of phase shift, nanoparticle volume fraction and Reynolds number on the streamline and temperature contours, local Nusselt number, local skin friction coefficient, average Nusselt number, non-dimensional pressure drop and thermalhydraulic performance factor have been presented and analyzed. Results indicate that the optimal performance is achieved by 01 phase shift channel over the ranges of Reynolds number and nanoparticles volume fractions.