Influence of Dental Prosthesis and Restorative Materials Interface on Oral Biofilms

Yu, Hao; Huang, Xiaoyu; Zhou, Xuedong; Li, Mingyun; Ren, Biao; Peng, Xian; Cheng, Lei

doi:10.3390/ijms19103157

Cited by 144 publications

(128 citation statements)

References 116 publications

(153 reference statements)

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“…Biofilm formation in the oral cavity is a gradated process, consisting of four stages, of which the initial bacterial adhesion and colonization are crucial steps (Hao et al, 2018).…”

Section: ])mentioning

confidence: 99%

The Impact of Smoking on Subgingival Microflora: From Periodontal Health to Disease

Jiang

Cheng

2020

Front. Microbiol.

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Periodontal disease is one of the most common diseases of the oral cavity affecting up to 90% of the worldwide population. Smoking has been identified as a major risk factor in the development and progression of periodontal disease. It is essential to assess the influence of smoking on subgingival microflora that is the principal etiological factor of the disease to clarify the contribution of smoking to periodontal disease. Therefore, this article reviews the current research findings regarding the impact of smoking on subgingival microflora and discusses several potential mechanisms. Cultivationbased and targeted molecular approaches yield controversial results in determining the presence or absence of smoking-induced differences in the prevalence or levels of certain periodontal pathogens, such as the "red complex." However, substantial changes in the subgingival microflora of smokers, regardless of their periodontal condition (clinical health, gingivitis, or periodontitis), have been demonstrated in recent microbiome studies. Available literature suggests that smoking facilitates early acquisition and colonization of periodontal pathogens, resulting in an "at-risk-forharm" subgingival microbial community in the healthy periodontium. In periodontal diseases, the subgingival microflora in smokers is characterized by a pathogen-enriched community with lower resilience compared to that in non-smokers, which increases the difficulty of treatment. Biological changes in key pathogens, such as Porphyromonas gingivalis, together with the ineffective host immune response for clearance, might contribute to alterations in the subgingival microflora in smokers. Nonetheless, further studies are necessary to provide solid evidence for the underlying mechanisms.

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“…Biofilm formation in the oral cavity is a gradated process, consisting of four stages, of which the initial bacterial adhesion and colonization are crucial steps (Hao et al, 2018).…”

Section: ])mentioning

confidence: 99%

The Impact of Smoking on Subgingival Microflora: From Periodontal Health to Disease

Jiang

Cheng

2020

Front. Microbiol.

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“…The physical and chemical characteristics of each material influence the pellicle and biofilm formation and might also have an influence on HAP deposition [35]. Comparisons between all materials showed that ceramic samples had the smallest quantity of HAP accumulated after 2 h (Figure 7), while the PMMA samples presented higher numbers of particles and clusters after the same time (Figure 8).…”

Section: Hydroxyapatite Adhesion Efficacymentioning

confidence: 99%

Adhesion of Hydroxyapatite Nanoparticles to Dental Materials under Oral Conditions

2020

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Hydroxyapatite nanoparticles (nano-HAP) are receiving considerable attention for dental applications, and their adhesion to enamel is well established. However, there are no reports concerning the effects of HAP on other dental materials, and most of the studies in this field are based on in vitro designs, neglecting the salivary pellicle-apatite interactions. Thus, this in situ pilot study aims to evaluate the effects of three hydroxyapatite-based solutions and their interactions with different dental material surfaces under oral conditions. Hence, two volunteers carried intraoral splints with mounted samples from enamel and from three dental materials: titanium, ceramics, and polymethyl-methacrylate (PMMA). Three HAP watery solutions (5%) were prepared with different shapes and sizes of nano-HAP (HAP I, HAP II, HAP III). After 3 min of pellicle formation, 10 ml rinse was performed during 30 sec. Rinsing with water served as control. Samples were accessed immediately after rinsing, 30 min and 2 h after rinsing. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to characterize the particles, and SEM evaluated the pellicle-HAP interactions. SEM and TEM results showed a high variation in the size range of the particles applied. A heterogeneous HAP layer was present after 2 h on enamel, titanium, ceramics, and PMMA surfaces under oral conditions. Bridge-like structures were visible between the nano-HAP and the pellicle formed on enamel, titanium, and PMMA surfaces. In conclusion, nano-HAP can adhere not only to enamel but also to artificial dental surfaces under oral conditions. The experiment showed that the acquired pellicle act as a bridge between the nano-HAP and the materials’ surface.

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“…It was reported that zirconium-niobium (Zr-Nb) alloys possessed better corrosion resistance and similar biocompatibility compared to Ti-6Al-4V and pure Ti [8,9]. Moreover, some new studies have shown that bacteria attached to zirconium implants poorly compared to titanium ones [10].…”

Section: Introductionmentioning

confidence: 99%

Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles

et al. 2020

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High strength, excellent corrosion resistance, high biocompatibility, osseointegration ability, and low bacteria adhesion are critical properties of metal implants. Additionally, the implant surface plays a critical role as the cell and bacteria host, and the development of a simultaneously antibacterial and biocompatible implant is still a crucial challenge. Copper nanoparticles (CuNPs) could be a promising alternative to silver in antibacterial surface engineering due to low cell toxicity. In our study, we assessed the biocompatibility and antibacterial properties of a PEO (plasma electrolytic oxidation) coating incorporated with CuNPs (Cu nanoparticles). The structural and chemical parameters of the CuNP and PEO coating were studied with TEM/SEM (Transmission Electron Microscopy/Scanning Electron Microscopy), EDX (Energy-Dispersive X-ray Dpectroscopy), and XRD (X-ray Diffraction) methods. Cell toxicity and bacteria adhesion tests were used to prove the surface safety and antibacterial properties. We can conclude that PEO on a ZrNb alloy in Ca–P solution with CuNPs formed a stable ceramic layer incorporated with Cu nanoparticles. The new surface provided better osteoblast adhesion in all time-points compared with the nontreated metal and showed medium grade antibacterial activities. PEO at 450 V provided better antibacterial properties that are recommended for further investigation.

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Influence of Dental Prosthesis and Restorative Materials Interface on Oral Biofilms

Cited by 144 publications

References 116 publications

The Impact of Smoking on Subgingival Microflora: From Periodontal Health to Disease

The Impact of Smoking on Subgingival Microflora: From Periodontal Health to Disease

Adhesion of Hydroxyapatite Nanoparticles to Dental Materials under Oral Conditions

Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles

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