Influence of Diabetes and Hemodialysis against Nerve Conduction Studies

Kato, Yukio; Bando, Hiroshi; Fujikawa, Tomomi; Narutaki, Miyuki; Yamamoto, Masami; Kakutani, Hideki; Shirai, Yujiro; Ishikura, Kazuyo; Kusunoki, Kazuhiro; Tanaka, Saeri; Kawata, Takafumi; Kanazawa, Setsuko; Matsuzaki, Sayuri; Bando, Masahiro; Waka, Shinnichi

doi:10.4172/2329-9126.1000343

Cited by 3 publications

(6 citation statements)

References 36 publications

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“…In our study, there were four groups, which are 1) Both DM/HD, 2) DM only, 3) HD only, 4) control. The results of SNCV and SNAP showed from abnormal to normal in group 1,2,3,4, respectively, in this order [3].…”

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confidence: 58%

“…Two conditions would be shown which are easy to understand. One is the research for DSPN, in which Sural Nerve Conduction Velocity (SNCV) and Sural Nerve Action Potential (SNAP) were measured in patients with Diabetes Mellitus (DM), Hemodialysis (HD) and control r [3]. In our study, there were four groups, which are 1) Both DM/HD, 2) DM only, 3) HD only, 4) control.…”

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confidence: 98%

“…As a result, patients with NDS>2 and Sensory NCV of Sural Nerve (SNCV) <42 m/s usually estimated as the presence of the neuropathy. This criteria have been applied for lots of reports about neuropathy [3].…”

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confidence: 99%

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Diabetic Peripheral Neuropathies (DPNs) from Basic and Clinical Aspects

Bando

2019

JOD

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Diabetes has been one of the crucial diseases worldwide, which has to be controlled adequately for long years. It has three diabetic complications of micro-angiopathy such as neuropathy, retinopathy and nephropathy. Among them, Diabetic Peripheral Neuropathies (DPNs) are most prevalent to manage in primary care setting. In this article, recent topics concerning DPNs are introduced [1]. DPNs have a variety of symptoms and signs, then DPNs are often described in plural forms [2]. DPNs are classified into two categories, which are local and general. The former includes mononeuropathy and multifocal neuropathy. The latter includes diabetic polyneuropathy (DPN) and others. DPN has Distal Symmetric Polyneuropathy (DSPN) and Diabetic Autonomic Neuropathy (DAN) [2]. For examples, DSPN shows bilateral numbness of extremities and DAN shows Orthostatic Hypotension (OH).

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confidence: 58%

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confidence: 98%

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Diabetic Peripheral Neuropathies (DPNs) from Basic and Clinical Aspects

Bando

2019

JOD

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“…Our medical group has been involved in dialysis treatment for many patients with chronic renal failure for years. We have continued some research studies concerning patients on hemodialysis [5][6][7]. We have conducted a study that combined the above-mentioned situations.…”

Section: Introductionmentioning

confidence: 99%

Carnitine for Body Composition in Hemodialysis Patients

Kakutani

Kato

Fujikawa

et al. 2020

EJBMR

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Background: Authors and colleagues have continued clinical research for hemodialysis patients. Currently, a pilot study presents intervention of carnitine for changes of the body composition. Subjects and Methods: Subjects were six patients on hemodialysis with intervention of carnitine (group 1). Average data were 74.3 years, 65.4 kg, 22.6 in BMI. As levocarnitine, L-Cartin FF injection 1000 mg was administered three times a week for six months. Group 2 has six control patients for age-, sex-, body weight, BMI-matched (group 2). Body composition of muscle and fat tissues were measured by InBody 770 on 0 and 6 months. Results: In group 1, muscle volume and skeletal muscle showed increasing tendency without statistical significance. In contrast, there were significant decreases of body fat volume (22.3 kg vs 20.5 kg, 39.0% vs 35.8%) (p<0.05). No significant differences were found in hemoglobin, total protein, albumin and Cardio-Thoracic Ratio (CTR) of chest X-ray. Group 2 showed no significant changes. Discussion and Conclusion: Hemodialysis patients often have muscular reduction. Previous reports showed improved lean body mass by carnitine administration, which may support our result. These results from current pilot study would be expected to become useful reference data in the pathophysiological investigation in patients on hemodialysis.

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“…[17][18][19] We have continued to treat a large number of diabetic patients and have published various reports. 20,21 Among them, some staffs of our diabetes team had noticed that there were several cases where diabetes control becomes worse from the spring to the summer, 2019. It was speculated that the climate had been extremely hot for several months.…”

Section: Introductionmentioning

confidence: 99%