Influence of dietary lysine level on whole-body protein turnover, plasma IGF-I, GH and insulin concentration in growing pigs

Effects of dietary lysine levels and lighting conditions on intramuscular fat accumulation in growing pigs

“…This result is consistent with our previous observation (Kobayashi et al., 2012). As other studies have also shown that low dietary lysine reduced circulating levels of insulin in pigs (Ren, Zhao, Li, & Meng, 2007; Roy, Lapierre, & Bernier, 2000), reduction of insulin levels due to low dietary lysine seems to be a reliable phenomenon. When 4‐month‐old pigs were fed a meal equivalent to approximately 1.5× their maintenance energy, the levels of insulin peaked within an hour after the feeding and returned to the pre‐feeding levels 6 hr post‐feeding (Metzler‐Zebeli et al., 2015).…”

Effects of Dietary Lysine Levels on the Plasma Concentrations of Growth‐Related Hormones in Late‐Stage Finishing Pigs

“…For example, the growing barrows fed diets containing 0.45 and 0.75% total lysine showed no difference in plasma insulin concentration, but the plasma insulin concentration was increased by 39% when dietary lysine concentration was raised to 0.98% [14]. Similarly, while the dietary concentration of total lysine at 0.71, 0.95, or 1.20% did not show any influence on plasma insulin concentration in growing pigs, 1.45% lysine in the diet significantly increased the plasma concentration of insulin [17]. In this present study on the late-stage finishing pigs, dietary lysine did not show any effect on the plasma insulin level, and there might be a few reasons responsible for the discrepancy between our results and those reported in the literature: (1) the late-stage finishing pigs may not be as sensitive as young humans or young growing pigs in response to AA stimulation, (2) our dietary lysine concentrations ( Table 1) might not be high enough to stimulate the release of insulin, and (3) the different blood sample collection time relative to the time of AA administration or feed intake might cause the differences.…”

“…According to some previous studies on growing pigs [14,17], dietary lysine supplementation stimulated the insulin secretion, increased the plasma insulin concentration, but not the plasma concentrations of GH and IGF-1, in a dosedependent manner. On nursery pigs, it was reported that the plasma IGF-1 concentration was reduced when animals were fed a diet lower in lysine level [18].…”

Sequences of digestible lysine for gilts from 60 to 148 days of age

“…Considering that among the studies mentioned above, in which lysine requirements were assessed considering the whole phase (growing to fi nishing), DE LA LLATA et al (2007) was the one assessing SIDL sequences at levels below the others, it can be concluded that this was a factor that may justify the difference seen among results. Investigating the effect of lysine levels (0.70, 0.95, 1.20, and 1.45%) on protein metabolism of growing pigs, REN et al (2007) observed that the increase in body protein deposition occurred only between the two lower levels of lysine. Furthermore, according to the authors, the increased lysine levels from 0.95 to 1.45% did not affect the synthesis and degradation of protein, hence pigs from the different treatments presented in a similar fashion maintaining unchanged body protein deposition, which is consistent with the results of DE LA LLATA et al (2007).…”