A study was conducted at college farm of Swami Keshwanand Rajasthan Agricultural University, Bikaner, Rajasthan, India to evaluate the influence of integrated application of different nutrient sources on growth, yield and nutrient content of wheat (Triticum aestivum L). Experiment was conducted in a randomized block design with three replications. Under different nutrient sources, i.e. control, 50 to 100% RDF, FYM 5 t ha-1, biofertilizers and their combined application were done. Findings exhibits that the application of 75 % RDF+5 t FYM ha-1+Azotobacter+PSB in wheat, significantly enhanced all growth (dry matter, chlorophyll content, total tillers, CGR, RGR and others) & yield attributes (Effective tillers, test weight and others), grain yield (4.12 t ha-1) and as quality, nutrient (N, P, K) content and protein content of wheat over rest of treatments, but it remained statistically at par with 100 % RDF+5 t FYM ha-1+ Azotobacter+PSB (grain yield 4.18 t ha-1). Thus, it is concluded that for better nutrient management, an integration of organic, inorganic and biofertilizers sould be done. With application of 75 % RDF+5 t FYM ha-1+Azotobacter+PSB, there is 25% saving of nutrients as compared to 100 % RDF+5 t FYM ha-1+ Azotobacter+PSB.