Numerical simulations, using the Ansys AUTODYN program, of Panzerfaust 30 (klein) anti-tank warhead, were performed to determine the influence of different liner materials on the penetration depth into a steel target. It has been shown that the choice of liner material can significantly affect the performance of the ammunition. Along with other methods of optimizing shaped charge ammunition (optimization of the shape, thickness and angle of the tip of the liner, use of more potent explosive and deviator, optimization of casing thickness and stand-off distance, etc.), the use of appropriate liner material is certainly one of the most important parameters of shaped charge warheads to consider. Together with analytical calculations and experimental tests, simulations are a valuable tool. Using data obtained from numerical simulations, researchers can save both time and resources during the process of munition design and optimization.