Influence of exogenous progesterone on survival of asynchronously transferred Day-10 horse embryos

Wilsher, S.; Clutton-Brock, Amber; Allen, William R.

doi:10.1016/j.jevs.2012.05.039

Cited by 1 publication

(2 citation statements)

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“…This advance in uterine age leads to increased pregnancy rates for transferred asynchronous embryos that would otherwise not survive (Wilsher et al . ). Thus, it is not the amount of progesterone but the length of exposure to it that triggers these events.…”

Section: Embryo‐uterine Synchronymentioning

confidence: 97%

“…Interestingly, administration of exogenous progesterone to mares from the day of ovulation hastens and augments their post ovulatory progesterone rise to the extent that their serum levels exceed 1 ng/mL on the day of ovulation, a full day ahead of untreated mares (Fig 9). This advance in uterine age leads to increased pregnancy rates for transferred asynchronous embryos that would otherwise not survive (Wilsher et al 2012b). Thus, it is not the amount of progesterone but the length of exposure to it that triggers these events.…”

Section: Embryo-uterine Synchronymentioning

confidence: 99%

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The uterus and early pregnancy failure in the mare

Wilsher

2017

Equine Veterinary Education

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Summary The environment the equine conceptus finds itself in when it arrives in the uterus some 6 days after ovulation will determine if it will thrive or die. The uterus will be its home for approximately the next 11 months and as such it needs to both coordinate the growth of the placenta and ensure there is enough nourishment passing to this organ for the fetus to develop normally. The trophoblast, endometrium, maternal ovaries and, later in pregnancy, the fetal gonads, all play roles in the hormonal changes that orchestrate these events. Although failures of these processes later in pregnancy can have catastrophic effects for the fetus, it is in early gestation that the foundations for a successful pregnancy are laid. This paper therefore concentrates on some of the noninfectious influences the uterus may have on survival of the young conceptus.

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Section: Embryo‐uterine Synchronymentioning

confidence: 97%

Section: Embryo-uterine Synchronymentioning

confidence: 99%