Influence of functional tricuspid regurgitation on right ventricular function

Sugimoto, Takeshi; Okada, Masayoshi; Ozaki, Nobuchika; Kawahira, Toshihiro; Fukuoka, Masato

doi:10.1016/s0003-4975(98)01041-8

Cited by 19 publications

(19 citation statements)

References 13 publications

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“…In PHTN-FTR, with large volume overload, RV FS remains high, and RV dysfunction may be undetected by casual examination. 41 Furthermore, RV remodeling is radically different in Id-FTR and PHTN-FTR, despite similar ERO with valvular-ventricular complex alterations specific of each FTR type.…”

Section: Right Ventricular Alterations In Functional Tricuspid Regurgmentioning

confidence: 96%

Clinical Context and Mechanism of Functional Tricuspid Regurgitation in Patients With and Without Pulmonary Hypertension

Topilsky

Khanna

Tourneau

et al. 2012

Circ: Cardiovascular Imaging

255

149

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Section: Right Ventricular Alterations In Functional Tricuspid Regurgmentioning

confidence: 96%

Clinical Context and Mechanism of Functional Tricuspid Regurgitation in Patients With and Without Pulmonary Hypertension

Topilsky

Khanna

Tourneau

et al. 2012

Circ: Cardiovascular Imaging

255

149

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“…15 It has been reported that functional TR may produce an irreversible deterioration of RV function. 16 Furthermore, RV dilation and systolic dysfunction can be resolved after TV surgery in isolated TR. 17 These results suggest that TV surgery probably should be recommended at a certain time even if a patient does not complain of any symptoms.…”

Section: Isolated Tricuspid Regurgitationmentioning

confidence: 99%

Long-Term Prognosis of Isolated Significant Tricuspid Regurgitation

Lee

Song

Park

et al. 2010

Circ J

159

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Background:The prognostic implications and surgical benefit of isolated significant tricuspid regurgitation (TR) and prognostic factors in patients with TR were investigated. Methods and Results:In 870 consecutive patients with significant isolated TR, all-cause mortality was analyzed over 4.9±2.9 years. It was found that the survival rate tended to be higher in the 57 patients who underwent tricuspid valve (TV) surgery than the 813 patients who did not by using propensity-score matching (P=0.068), although it was not significant. Of the 813 patients that did not undergo TV surgery, the 5-year survival rate was 74%. According to the Cox proportional hazards model, the initial TR jet area (hazard ratio [HR], 1.044; 95% confidence interval [CI], 1.016-1.073), pulmonary artery systolic pressure (HR, 1.024; 95%CI, 1.017-1.032) and presence of right ventricular (RV) dysfunction (HR, 2.256; 95% CI, 1.329-3.828) were predictors of mortality independent of patient age and presence of diabetes mellitus and renal failure in medically managed patients. Conclusions:In patients with isolated significant TR, there was a tendency, although not significant, towards a higher survival rate after TV surgery. The severity of TR and pulmonary hypertension, and the presence of RV dysfunction are independent prognostic factors in medically managed patients. Further prospective randomized studies are necessary to demonstrate the benefit of TV surgery in these poor prognostic populations. (Circ J 2010; 74: 375 - 380)

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“…Cardiomegaly because of right heart failure with pulmonary hypertension might cause leaflet tethering, which is a recognized risk factor for an unfavorable result after tricuspid annuloplasty. 4,19 Our findings indicate that tricuspid annuloplasty alone might not be sufficient to eliminate functional TR in patients with preoperative advanced right heart failure. In addition, we found that early residual TR and Af are risk factors for significant residual TR after annuloplasty, which concurs with the findings of previous investigations of other methods of tricuspid annuloplasty and suggests that patients with persistent right ventricular dysfunction or Af may require additional repair or other types of procedures to correct the abnormalities of the ventricle, despite the use of the new 3-D annuloplasty ring.…”

Section: Discussionmentioning

confidence: 81%

“…18,19 However, when left untreated, a significant number of patients develop severe symptomatic TR over time. 6,9 Furthermore, development of significant late functional TR jeopardizes long-term outcomes.…”

Section: Discussionmentioning

confidence: 99%

Tricuspid Annuloplasty Using the MC3 Ring for Functional Tricuspid Regurgitation

Jeong

Kim

2010

Circ J

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Background:A recently introduced tricuspid annuloplasty ring, the MC 3 ring, has a 3-dimensional form that is designed to remodel the tricuspid valve annulus. The aim of this study was to investigate its clinical performance. Methods and Results:From December 2004 to April 2008, 103 patients underwent tricuspid annuloplasty using the MC 3 ring (mean age, 52±13 years; 63.6% women). The average preoperative tricuspid regurgitation (TR) grade was 2.5±0.8, and the mean preoperative systolic pulmonary artery pressure was 48.4±15.0 (24-88) mmHg; the mean follow-up was 26.7±11.2 (0-52) months. One patient died after surgery (1.0%), because of cor pulmonale. No MC 3 ring-related complications, such as, atrioventricular block, ring dehiscence or thromboembolism, were encountered. Predischarge echocardiography showed a significant decrease in the TR grade (2.5±0.8 to 0.8±0.8, respectively; P<0.001). After a median 15 months, the mean TR grade was stable (0.9±0.8). The mean systolic pulmonary artery pressure was also lower than its preoperative value (33.9±7.9 vs 48.4±15.0 mmHg, respectively; P<0.001). Conclusions:The MC 3 ring provides good mid-term clinical and echocardiographic results for TR. However, long-term follow-up is mandatory to confirm the stability of this procedure. (Circ J 2010; 74: 278 - 283)

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Influence of functional tricuspid regurgitation on right ventricular function

Cited by 19 publications

References 13 publications

Clinical Context and Mechanism of Functional Tricuspid Regurgitation in Patients With and Without Pulmonary Hypertension

Clinical Context and Mechanism of Functional Tricuspid Regurgitation in Patients With and Without Pulmonary Hypertension

Long-Term Prognosis of Isolated Significant Tricuspid Regurgitation

Tricuspid Annuloplasty Using the MC3 Ring for Functional Tricuspid Regurgitation

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