With the growing demands in several sectors such as the automotive, biomedical, construction, shipbuilding, aerospace, and other manufacturing units, employment of welding techniques has observed a rapid boom in recent times. Laser welding technique is one such recent sign of progress in the fabrication field. Laser beam welding is a radiant energy welding process widely adapted to join a variety of metals and nonmetals. The demand for the dissimilar material welding increases with the increase in industrial needs. Several severe challenges need to be overcome to have such dissimilar welded components mainly as the significant difference in melting point, different combinations of mechanical, metallurgical, chemical, and thermal properties. The present approach attempts to study the weldability of steel and its alloys with other metals and parametric effects on mechanical and microstructural properties. The study reveals that the laser beam offset plays a vital role to achieve sound quality welded joint with desirable weld strength. It has been found that 0.32 mm beam offset generates 243 MPa ultimate tensile strength in the 316L to TC4 dissimilar welds. Again, the addition of interlayers also improves the joint strength of both steel‐to‐aluminum and steel‐to‐titanium dissimilar welded joints.