In this research, persimmon samples (sliced, pureed) were dehydrated by convective (50 and 100°C) and microwave (100 W) drying techniques with different pre-treatment combinations of sugar addition (25%) and blanching (100°C, 5 min). Each pre-treatment consisting of sugar addition, slicing, and blanching resulted in a significant increase in color parameters compared to unpretreated samples. Color parameters measured at low drying temperatures were lower than high ones. Also, 100 W dried samples were higher in total anthocyanin content, and the pureed samples were 24.80% higher than sliced ones. The bioactive potential was evaluated regarding extractable, hydrolysable, and bioaccessible phenolic fractions (EPF, HPF, BPF) by total phenolic content and ABTS, CUPRAC, and DPPH antioxidant capacity assays. i) 50°C drying prevailed on drying at 100°C and 100 W, especially in terms of EPF and BPFs; ii) Sliced samples were higher for EPF and BPF, while pureed ones were higher in HPFs; iii) Blanched samples were relatively higher than unblanched ones in TPC. For antioxidant capacity assays, EPFs were higher in blanched samples and BPF in unblanched ones (TEACABTS, TEACCUPRAC). iv) Sugar addition negatively affected the bioactive potential in persimmon samples; no-sugar-added samples were higher, especially in BPF (p < 0.01; TPC, TEACABTS, TEACCUPRAC). v) The CUPRAC assay was the most appropriate method due to providing a view of more statistical distinction by picturing the same potential.