Influence of hemorrhage and subsequent fluid resuscitation on transcranial motor-evoked potentials under desflurane anesthesia in a swine model

Kurita, Tadayoshi; Kawashima, Shuichi; Khaleelullah, Mohamed Mathar Sahib Ibrahim; Nakajima, Yoshiyuki

doi:10.1007/s10877-020-00644-2

Cited by 2 publications

(1 citation statement)

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“…Due to anatomical and technical features, pig intubation is still complicated even for experienced professionals, requiring an average of 1.2 attempts for successful intubation (Janiszewski et al, 2014). The best intubation recumbency (Theisen et al, 2009), the use of a plastic guide (Hartmann et al, 1971) and the best anaesthesia protocols are still being developed and complications described in order to improve the intubation of pigs (Zigmantaite et al, 2018) (Kurita et al, 2022). Ketamine is the primary anaesthetic drug, mainly used for pig anaesthesia; a well-known ketamine potential side effect is hypersalivation, which can lead to laryngospasm (Heinz et al, 2006); therefore, the use of atropine in combination with ketamine is often recommended in anaesthesia protocols (Calzetta et al, 2014).…”

Section: Resultsmentioning

confidence: 99%

Effect of Atropine Sulphate on Laryngeal Accessibility and Visibility for Swine Intubation

Zigmantaitė

Jonušaitė

Grigalevičiūtė

et al. 2022

ASD

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Background: Animal intubation is necessary in painful surgery procedures in order to maintain general anaesthesia and analgesia. In swine, orotracheal intubation is difficult or impossible; all possible measures to improve it need to be explored. Methods: Two groups of a total of 20 clinically healthy local mixed breed (Sus scrofa domesticus) premedicated swine underwent intubation. The animals were randomly divided into two groups, one using atropine sulphate (A) and one using saline solution (N), prior to endotracheal intubation. Premedication started with intramuscular injection of xylazine, ketamine and fentanyl. Intubation was performed after induction with thiopental sodium administered intravenously with atropine sulphate or saline solution. Larynxes were photographed and filmed and coded images and videos were sent to investigators for evaluation. Result: In this study, a negative effect of atropine sulphate on the laryngeal visibility, opening and accessibility in local mixed breed anesthetized pigs was identified.

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